In a nutshell The study evaluated the effectiveness of aquatic therapeutic exercise in breast cancer survivors for improving symptoms and quality of life. The study found that aquatic therapeutic exercise effectively improved fatigue, pain, and quality of life in these patients. Some background Breast cancer (BC) is the most common...
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Can eye tumors be surgically removed without removing the entire eye?
In a nutshell This study looked at the effectiveness of a surgical treatment called partial transscleral sclerouvectomy (PTSU) combined with microinvasive vitrectomy and reconstruction of the eyeball (MIVR) for the treatment of tumors within the eyeball. This showed that this treatment can be effective for most eye tumors. Some background Melanoma is...
Read MoreEvaluating the benefits of allogeneic hematopoietic stem cell transplantation in childhood acute myeloid leukemia.
In a nutshell This study analyzed the use of allogeneic hematopoietic stem cell transplantation (alloHSCT) therapy following first remission in children with newly diagnosed, high-risk acute myeloid leukemia (AML) compared to chemotherapy. This study supports the use of alloHSCT for children with AML that are at greater. Some background Childhood AML...
Read MoreSafety and effectiveness of two different doses of daily-administered ABX464 in patients with unresponsive rheumatoid arthritis.
In a nutshell This study investigated the safety and effectiveness of ABX464 (Obefazimod) in patients with active rheumatoid arthritis (RA) with inadequate responses to methotrexate (Trexall) or anti-tumor necrosis factor alpha (anti-TNFα) treatment. The authors concluded that ABX464 was safe and well-tolerated with promising effectiveness in these...
Read MoreEvaluating the effectiveness and safety of replacing lenalidomide with pomalidomide for the treatment of patients with multiple myeloma who are unresponsive to a lenalidomide-containing combination regimen.
In a nutshell This study evaluated the effectiveness and safety of replacing lenalidomide (Revlimid) with pomalidomide (Pomalyst) for the treatment of patients with relapsed or refractory (r/r) multiple myeloma (MM) who were unresponsive to a lenalidomide-containing combination regimen. The data showed that pomalidomide was a safe and effective...
Read MoreEvaluating the effectiveness and safety of microwave ablation therapy for the treatment of lung metastases in patients with colorectal cancer.
In a nutshell This study evaluated the effectiveness and safety of microwave ablation (MWA) therapy for the treatment of lung metastases in patients with colorectal cancer (CRC). The data showed that MWA therapy might be a safe and effective option for these patients. Some background CRC is one of the most common types of cancer worldwide. Some...
Read MoreEvaluating the effectiveness and safety of penpulimab in patients with relapsed or refractory classical Hodgkin lymphoma.
In a nutshell This study evaluated the effectiveness and safety of penpulimab (AK105) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The data showed that penpulimab was effective and safe with manageable side effects in these patients. Some background Classical Hodgkin lymphoma (cHL) is a cancer of...
Read MoreEvaluating the effects of the plant-based polyphenol-rich extract TOTUM-63 on glucose control in patients with prediabetes or early-stage type 2 diabetes.
In a nutshell This study evaluated the effects of the plant-based polyphenol-rich extract TOTUM-63 on glucose control in patients with prediabetes or early-stage newly diagnosed type 2 diabetes (T2D). The data showed that TOTUM-63 was safe and lowered fasting blood glucose in these patients. Some background Patients with...
Read MoreEvaluating the effectiveness of three exercise programs and intensive follow-up in improving quality of life, pain, and lymphedema among breast cancer survivors
In a nutshell The study evaluated the effectiveness of three exercise programs in improving quality of life (QOL), pain, and lymphedema among breast cancer (BC) survivors. The study found that joint mobility exercise (JME) combined with progressive resistance exercise (PRE) showed promising results in improving QOL and lymphedema after BC...
Read MoreEvaluating the effectiveness and safety of Q-122 for menopausal symptoms in women with breast cancer taking hormonal treatment
In a nutshell The study evaluated the effectiveness and safety of Q-122, a new non-hormonal oral treatment for menopausal symptoms in women with breast cancer taking hormonal therapy. The study found that Q-122 is effective and safe in treating menopausal symptoms in these patients. Some background The treatment for hormone receptor-positive...
Read MoreEvaluating the effectiveness and safety of two consecutive cycles of single embryo transfer versus one cycle of double embryo transfer in infertile women.
In a nutshell This study evaluated the effectiveness and safety of two consecutive cycles of single embryo transfer (SET) versus one cycle of double embryo transfer (DET) in infertile women. The data showed that two consecutive cycles of SET significantly reduced the rate of multiple births, improved the maternal and neonatal side effects, and showed a...
Read MoreEvaluating the effectiveness and safety of mFOLFOXIRI chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer
In a nutshell This study evaluated the effectiveness and safery of administering modified (m) FOLFOXIRI (folinic acid, fluorouracil, irinotecan, oxaliplatin) chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer (LARC). The results showed that this treatment was safe and improved survival without disease...
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