In a nutshell The authors compared the incidence rates of moderate and severe hypoglycemia in traditional insulin pump therapy and sensor-augmented pump therapy. Some background Hypoglycemia (dangerously low blood glucose levels) is a critical obstacle to care of patients with type 1 diabetes. Type 1 diabetes patients require insulin therapy to...
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In a nutshell This study evaluated the association between age of onset and glycemic control in patients with type I diabetes mellitus. Some background Type I diabetes mellitus is an autoimmune disease in which there is an ongoing destruction of beta cells (cells found in the pancreas that produce insulin). The disease is...
Read MoreIn a nutshell This review explored whether strict glycemic control can reduce the risk of cardiovascular events among diabetic patients. Some background Hyperglycemia, or high blood glucose levels, can damage both large and small blood vessels. Damage to large blood vessels significantly elevates the risk for complications such as heart attacks or...
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In a nutshell This study evaluated whether an oral dose of sitagliptin was as effective as an injectable dose of liraglutide in patients with type 2 diabetes mellitus (T2DM) uncontrolled with metformin alone. Some background Patients with T2DM do not produce enough insulin (or are resistant to insulin) to break down the glucose they take in from...
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In a nutshell The present study compared the effects of therapy with either Metformin or Sulfonylureas (Glyburide, Glipizide) on cardiovascular events (heart attack and stroke) or death in patients with type 2 diabetes mellitus (DM2). The main findings were that treatment with Sulfonylurea was associated with an increased risk of cardiovascular disease...
Read MoreIn a nutshell The present study examined the effects of a long-term intensive weight-loss intervention (ILI) on type 2 diabetes mellitus (T2DM). ILI was associated with a greater probability of partial remission (fasting blood sugar <126 mg/dl) of diabetes, and a low prevalence of absolute remission (normal blood sugar levels). Some...
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The present review examined the effects of diabetes on the occurrence of osteoporosis (reduced bone mineral density-BMD) and fractures. Type 1 diabetes (T1DM) and type 2 diabetes (T2DM) are associated with a high risk of osteoporotic fractures but have different effects on the BMD. While in T1DM bone formation is damaged in T2DM the BMD is...
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