In a nutshell This study evaluated the safety and efficacy of Technosphere insulin in type 2 diabetic patients. Some background Current standards of care with type 2 diabetes focus on achieving and maintaining stringent glycemic (glucose) control. The use of prandial insulin (Humalog; taken at mealtimes) added to oral antidiabetic agents has...
Read MoreRecent HbA1C value-Above 7 Posts on Medivizor
Addition of insulin glargine to combination therapy with oral anti-diabetic drugs: a promising therapeutic option for type 2 diabetes
In a nutshell This study compared the effects of adding insulin glargine treatment to metformin (Glucophage), glimepiride (Amaryl) or their combination in patients with uncontrolled type 2 diabetes mellitus. Some background Hyperglycemia (high blood glucose) in type 2 diabetes mellitus arises from a combination...
Read MoreControlling uncontrolled diabetes
In a nutshell This review analyzed the effects of incretin based therapies in combination with insulin as treatment for uncontrolled type 2 diabetes mellitus (T2DM). Some background Non-insulin oral drugs, such as incretin based therapies, are a common treatment for T2DM patients. Incretins are hormones that are normally released by the body in...
Read MoreThe current state of pancreas transplantation
In a nutshell This review analyzed current research regarding pancreas transplantation for diabetic patients. Some background The hormone insulin is produced by the pancreas and is responsible for regulating blood sugar levels. In type 1 diabetes mellitus (T1DM), the pancreas does not produce insulin effectively. In type 2 diabetes mellitus...
Read MoreA comparison of the efficacy and safety of an oral versus an injectable treatment for patients with type 2 diabetes mellitus
In a nutshell This study evaluated whether an oral dose of sitagliptin was as effective as an injectable dose of liraglutide in patients with type 2 diabetes mellitus (T2DM) uncontrolled with metformin alone. Some background Patients with T2DM do not produce enough insulin (or are resistant to insulin) to break down the glucose they take in from...
Read MoreA variety of medications for type 2 diabetes: comparison of the efficacy and drawbacks
In a nutshell The aim of this review was to summarize the benefits and harms of several drugs commonly used for the treatment of adults with type 2 diabetes mellitus (T2DM). Some background Treatment for T2DM usually starts with diet changes and exercise because it is largely associated with obesity. Treating T2DM with medications aims to...
Read MoreLong acting insulin versus sitagliptin (Januvia) in type 2 diabetes not controlled with metformin (Glucophage) alone
In a nutshell This study compared the safety and efficacy of Insulin glargine (Lantus) versus Sitagliptin (Januvia) in the management of type 2 diabetes mellitus (T2DM) poorly controlled by Metformin (Glucophage) alone. Main findings: insulin glargine provides better glycemic control than Sitagliptin when added to Metformin therapy. Some...
Read MoreEfficacy and Safety of Dapagliflozin (Forxiga) in Type 2 Diabetics Treated with High Doses of Insulin
In a nutshell This trial assessed the efficacy and safety of a new diabetes drug, Dapagliflozin (Forxiga). Results revealed that the drug helps control difficult cases of type 2 diabetes with only moderate side-effects. Some background Dapagliflozin is a drug recently approved by the European Medicines Agency for the treatment of diabetes. Its...
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