In a nutshell This study investigated whether health-related changes to behaviour were associated with decreased cardiovascular risk in patients with type 2 diabetes Some background Healthy behavior changes include increased physical activity, improved diet and decreased alcohol intake. Such changes have previously been shown to have a beneficial...
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In a nutshell The aim of this study was to investigate the association of gender and various factors such as disease duration, age, blood sugar level and weight with gastroparesis in type 2 diabetes patients. Some background Some patients who have had type 2 diabetes for a long time can develop gastroparesis. Their stomach empties at an abnormally...
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In a nutshell This study investigated the effect of 3 different therapy combinations on the occurrence of cardiovascular disease in type 2 diabetes. Some background There are a number of types of drugs that can be used to treat diabetes. Metformin (Glucophage) decreases glucose production, and is often the first choice of treatment...
Read MoreIn a nutshell This trial investigated the relationship between weight loss, lower blood glucose (sugar) levels and lower blood pressure in type 2 diabetics treated with canagliflozin. Some background Many patients with type 2 diabetes (T2D) are overweight or obese. Losing weight is known to reduce or eliminate diabetes. Most of the current...
Read MoreIn a nutshell This study examined whether pregnant women who use an insulin pump have better control of blood glucose levels and better pregnancy outcomes in comparison to those using multiple daily injections. Some background 80% of infants born to women with type 1 diabetes (T1D) have at least one complication associated with maternal diabetes....
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In a nutshell This study examined the effects of adding dapagliflozin (Farxiga) in patients with uncontrolled type 2 diabetes despite taking metformin (Glucophage) plus a sulfonylurea (such as Amaryl or Glucotrol). Some background Metformin increases the body’s sensitivity to insulin, and is generally the...
Read MoreIn a nutshell This study aimed to compare the effects of bariatric surgery compared to medication in type 2 diabetes. Some background Type 2 diabetes is a long-term, progressive disease caused due to resistance to insulin. There are several ways to treat this disease, including surgery and medication. In obese patients, bariatric surgery is often...
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In a nutshell The authors compared the effectiveness of two long-acting insulins; insulin degludec (Tresiba) and insulin detemir (Levemir). Some background Basal-bolus insulin therapy in type 1 diabetes involves the use of a long-acting insulin dose (basal) to keep blood glucose levels stable through periods of fasting and a short-acting...
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In a nutshell The authors evaluated the risk of dysfunction of the optical nerves associated with the presence of diabetes. Some background Nonarteritic anterior ischemic optic neuropathy is the most common eye-related neuropathy (nerve damage or dysfunction) in people aged 50 and over. The medical condition involves loss of...
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In a nutshell This trial compared a combination of insulin degludec and insulin aspart with biphasic insulin aspart 30 in adults with type 2 diabetes. Some background Insulin is the most effective therapy for achieving glycemic (blood glucose) control in patients with type 2 diabetes, and due to the progressive nature of the disease, many type 2...
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In a nutshell This study evaluated the safety and effectiveness of once-daily insulin detemir and insulin glargine when added to metformin therapy in type 2 diabetes patients. Some background Initiating insulin therapy with a once-daily basal insulin therapy (long-acting insulins used to provide stable blood insulin levels throughout the day) in...
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In a nutshell The authors evaluated the impact of a moderate carbohydrate versus a low carbohydrate diet on blood glucose levels in type 2 diabetes and prediabetes. Some background Although there is agreement that diet is an important strategy for treating type 2 diabetes and prediabetes, there is little consensus about the optimal diet. Current...
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