In a nutshell This study examined the risk factors associated with peripheral neuropathy among young people with diabetes. The authors concluded that there is a high rate of neuropathy among young patients, and it is associated with cardiovascular risk factors. They suggested that certain lifestyle changes may reduce the risk. Some background...
Read MoreRecent HbA1C value-Above 7 Posts on Medivizor
Semaglutide is safe and effective as a second-line treatment in type 2 diabetes
In a nutshell This study compared the effectiveness and safety of two second-line therapies for type-2 diabetes. The authors concluded that once-weekly semaglutide was more effective than once-daily sitagliptin (Januvia); and that both drugs were safe. Some background The first-line treatment for patients with type 2 diabetes (T2D)...
Read MoreDoes the use of GLP-1RAs protect against later heart-disease?
In a nutshell This study examined whether the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) protected against later heart disease in type 2 diabetes. The authors concluded that GLP-1RAs significantly reduced the risk. Some background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are commonly used to treat type 2 diabetes...
Read MoreCan intensive control of blood sugar help prevent kidney, eye, and nerve complications?
In a nutshell This study assessed the potential benefits of controlling blood sugar to a strict level. The authors concluded that intensive blood-sugar control prevented kidney and eye complications, but not nerve complications. Some background Poorly-managed...
Read MoreDoes fast-acting insulin aspart improve blood sugar control in type 2 diabetes?
In a nutshell This study investigated if administering fast-acting insulin aspart (faster aspart) at mealtimes improved glycemic control in patients with type 2 diabetes. They found that faster aspart improved glycemic control compared to basal (long-lasting) insulin alone, but with increased hypoglycemia and weight gain. Some background...
Read MoreDo smaller late-night meals improve blood sugar increases in patients with type 2 diabetes?
In a nutshell This study examined if eating a divided dinner late at night had an impact on blood sugar levels in patients with type 2 diabetes. They found that patients who ate a divided meal late at night improved increased blood sugar (hyperglycemia) following the meal (postprandial). Some background Postprandial hyperglycemia refers to...
Read MoreIs there a benefit to switching to insulin pump therapy in patients with type 1 diabetes?
In a nutshell This study investigated the effects of switching from multiple insulin injections to a continuous insulin pump in patients with type 1 diabetes. They concluded that insulin pump therapy effectively improved blood sugar control in patients with type 1 diabetes who switched from multiple daily insulin injections. Some background...
Read MoreIs insulin degludec more effective than insulin glargine U100 at reducing hypoglycemia in patients with type 2 diabetes?
In a nutshell This study investigated the effects of insulin degludec (Tresiba) versus insulin glargine U100 (Lantus) on hypoglycemia (low blood sugar) in patients with type 2 diabetes. They found the number of hypoglycemic episodes was significantly lower in patients receiving insulin degludec. Some background Insulin therapy is a...
Read MoreIs empagliflozin effective as an add-on therapy in uncontrolled type 2 diabetes?
In a nutshell This study determined the suitability of adding empagliflozin (Jardiance) to the combination of metformin (Glucophage) and linaglipton (Tradjenta) in type 2 diabetes. The authors concluded that adding empagliflozin was effective in patients whose blood sugar was not controlled by the combination of metformin and linaglipton alone. Some...
Read MoreAre vildaglipton and insulin used together better for treating type 2 diabetes?
In a nutshell This study examined whether vildagliptin (Galvus) added to insulin treatment was safe and effective over the long term. The study concluded that vildagliptin in addition to insulin was effective and well tolerated by type 2 diabetes patients. Some background Patients with type 2 diabetes...
Read MoreGlucagon-like peptide 1 receptor agonists investigated in people with type 2 diabetes
In a nutshell This article compared the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to insulin in patients with type 2 diabetes (T2D). The study concluded that weekly GLP-1 RAs were more effective in controlling blood glucose, and that all GLP-1 RAs reduced weight, compared to insulin. Some background T2D is a progressive...
Read MoreGemigliptin effective as part of combination drug therapy in type 2 diabetes
In a nutshell This study examined the impact of gemigliptin as part of a combination with metformin (Glucophage) and glimepiride (Amaryl) in patients with type 2 diabetes (T2D). The study found that gemigliptin was effective in the management of T2D in combination with metformin and glimepiride. Some background...
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