In a nutshell This paper reviewed what recurrent implantation failure is and how it can be treated. Some background Implantation is the process where the embryo attaches to the outer layer of the uterus and moves into the deeper layer of the uterus. Recurrent implantation failure occurs when implantation repeatedly fails. Methods &...
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Will increasing the dose of follicle stimulating hormone affect the outcome in assisted reproduction?
In a nutshell This paper studied the effect of different amounts of recombinant human follicle stimulating hormone in patients undergoing assisted reproduction. Some background Ovarian stimulation is a technique where medications are used to stimulate the release of eggs in assisted reproduction. Recombinant human follicle-stimulating...
Read MoreCan micro-testicular sperm extraction help with pregnancy in Klinefelters Syndrome?
In a nutshell This paper studied the performance of microsurgical testicular sperm extraction in patients with Klinefelter syndrome. Some background Klinefelter syndrome is caused by an abnormal number of chromosomes. This causes nonobstructive azoospermia (lack of sperm in semen). Klinefelter Syndrome is associated with infertility and...
Read MoreCan treating sleep disturbance increase testosterone levels?
In a nutshell This paper studied whether treating nocturia increased testosterone levels in men with hypogonadism (insufficient production of testosterone). Some background Nocturia (having to wake up and urinate at night) leads to sleep disturbances. This can affect testosterone (a sex hormone) secretion. Testosterone contributes to sperm...
Read MoreAre there risks associated with intrauterine insemination?
In a nutshell This paper studied the perinatal effects on babies conceived through intrauterine insemination. Some background Intrauterine insemination is a fertility treatment where fast moving sperm are placed into the woman's womb close to the time when the egg is released from the ovary in the middle of the monthly cycle. Artificial...
Read MoreWhen the testes fail, does treatment with gonadotrophins help?
In a nutshell This paper studies the effect of gonadotrophin treatment on quality of life compared with testosterone treatment in patients with male hypogonadotrophic hypogonadism (failure of the testes). Some background Male hypogonadotrophic hypogonadism is the failure of the testes that results in a decrease of testosterone and...
Read MoreThe best sperm retrieval technique for men with reduced sperm production
In a nutshell This article reviewed currently published data concerning the efficacy and safety of the different sperm retrieval techniques for men with reduced sperm production. Some background Around 10% of infertile men suffer from non-obstructive azoospermia, which describes a condition in which very few sperm cells are produced in the...
Read MoreDoes progesterone level affect the success of in vitro fertilization?
In a nutshell This study examined whether progesterone levels have an effect on live birth rates in women undergoing in vitro fertilization. Some background For a successful pregnancy to occur with an assisted reproductive technique such as in vitro fertilization (IVF; the egg is fertilized outside of the body and implanted into the uterus), the...
Read MoreA more effective treatment to trigger ovulation
In a nutshell The current study examined the safety and efficacy of letrozole (Femara) for ovulation induction in women with polycystic ovarian syndrome. Some background Polycystic ovarian syndrome is the most common cause of infertility due to non-ovulation. The first treatment for women with polycystic ovarian syndrome trying to achieve...
Read MoreThe timing of Clomid could increase ovulation and pregnancy rates
In a nutshell This study examined whether the timing of clomiphene citrate affects ovulation and pregnancy rates in women with polycystic ovarian syndrome. Some background Polycystic ovarian syndrome is the most common cause of anovulation, or lack of regular ovulation. Women with polycystic ovarian syndrome are at a high risk...
Read MoreWhen IVF fails: factors associated with treatment failure
In a nutshell This study examined the factors associated with the chances of in vitro fertilization failure. Some background In vitro fertilization, or IVF, is a fertility treatment in which an egg is fertilized by sperm outside of the body. While IVF is often recommended as a treatment for couples struggling with infertility, only 32%...
Read MoreImportance of ultrasound guidance during intrauterine insemination
In a nutshell This study evaluated the effects of ultrasound guidance during intrauterine insemination (IUI) on pregnancy rates. The impact of physician experience on intrauterine insemination success was also assessed. Some background Intrauterine insemination is often the first treatment attempted by couples experiencing unexplained infertility....
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