In a nutshell This study investigated if the long-term development of children is affected by the type of embryo transfer (ET). They found that there were similar outcomes with fresh (fr) and frozen (fz) ET. Some background Assisted reproduction (AR) is used to treat infertility. It has become more common in recent years. There are a number of...
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Overview of ovarian stimulation for assisted reproduction
In a nutshell This article gives an overview of ovarian stimulation (OS) during assisted reproductive techniques (ART). Some background Many couples with infertility opt to use ART. In vitro fertilization (IVF) is an ART in which eggs are collected and fertilized embryos are implanted in the uterus. The first step of IVF is to cause...
Read MoreMaximizing IVF egg production for women with low ovarian reserve
In a nutshell This study compared in vitro maturation (IVM) to double ovarian stimulation (DuoStim) for women expected to have a poor outcome from in vitro fertilization (IVF). It found that both methods increased the number of eggs compared to standard IVF, and that DuoStim may be more effective. Some background The first step of the infertility...
Read MoreDoes in vitro fertilization affect cardiovascular function in women?
In a nutshell This study investigated if cardiovascular function (CVF) is altered by in vitro fertilization (IVF). They found that IVF may cause short-term changes to CVF in women. Some background In vitro fertilization (IVF) is used to treat infertility. The first step of IVF involves harvesting eggs. Women inject hormones to stimulate the...
Read MoreCan oocyte activation improve ICSI outcomes?
In a nutshell This study looked at activating oocytes (eggs) with calcium ions prior to intracytoplasmic sperm injection (ICSI). It found that this treatment improves fertilization rates for couples with male infertility, and may improve pregnancy rates. Some background ICSI is an infertility treatment used when there are few sperm available. It...
Read MoreDoes melatonin treatment improve fertility outcomes in assisted reproduction?
In a nutshell This study investigated if melatonin improves fertility outcomes in assisted reproduction (AR). They found that melatonin improved the clinical pregnancy rate (CPR) in AR cycles. Some background Infertility is becoming increasingly common. Assisted reproduction (AR) can be used to treat infertility. Many studies have been conducted...
Read MoreHow safe and effective is anti-Mullerian hormone-based ovarian stimulation?
In a nutshell This study investigated if anti-Mullerian hormone (AMH) measuring is useful in controlled ovarian stimulation (COS). They found that pregnancy rates with AMH-COS were similar to standard COS (sCOS). Some background Controlled ovarian stimulation (COS) is the first step in assisted reproduction (AR). COS is performed to retrieve...
Read MoreAre IVF trigger hormone levels associated with pregnancy rates?
In a nutshell This study looked at whether blood levels of the HCG hormone affect the chances of pregnancy after in vitro fertilization (IVF). This study concluded that having high HCG levels in the blood was associated with a higher chance of pregnancy. Some background IVF is an infertility treatment in which eggs are removed from a...
Read MoreDoes low dose hCG improve fertility outcomes in women with polycystic ovarian syndrome?
In a nutshell This study investigated the effect of low dose human chorionic gonadotrophin (hCG) in women with polycystic ovarian syndrome (PCOS). They found that hCG may improve the number of follicles and clinical pregnancy rates (CPR) in women with PCOS. Some background Polycystic ovarian syndrome (PCOS) is a common condition...
Read MoreAge and infertility treatment – do women with polycystic ovarian syndrome have an advantage?
In a nutshell This study investigated the effect of age on infertility treatment in women with polycystic ovarian syndrome (PCOS). They found that age-related decline (ARD) in fertility treatment outcomes was slower in women with PCOS. Some background Polycystic ovarian syndrome (PCOS) is caused by cysts on the ovaries. Women with PCOS have...
Read MoreReview of treatment options for couples experiencing infertility
In a nutshell This article reviewed different treatment options for couples experiencing infertility. Some background Infertility affects approximately 1 in 7 couples trying to conceive. Treatment of infertility depends on the cause. Men, women or both partners can have symptoms of infertility. In women, infertility can be due...
Read MoreInvestigating the effectiveness of a letrozole ‘step-up’ protocol for controlled ovarian stimulation
In a nutshell This study investigated the effect of a letrozole (Femara) step-up protocol (SUP) for controlled ovarian stimulation (COS). They found that a letrozole-SUP was as effective as standard COS protocol and less costly. Some background Unexplained infertility (UI) is increasingly common. Women with UI usually have a normal...
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