In a nutshell This study evaluated the effectiveness and safety of two consecutive cycles of single embryo transfer (SET) versus one cycle of double embryo transfer (DET) in infertile women. The data showed that two consecutive cycles of SET significantly reduced the rate of multiple births, improved the maternal and neonatal side effects, and showed a...
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Comparing the effectiveness of IVF/ICSI versus IUI in unexplained infertility
In a nutshell The study compared the pregnancy rates for intrauterine insemination (IUI) and in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in couples with unexplained infertility. The data concluded that IVF/ICSI is a better treatment option than IUI for unexplained infertility. Some background Infertility is the inability to...
Read MoreEvaluating the effectiveness of intralipid administration to improve in vitro fertilization outcomes
In a nutshell The study evaluated the effectiveness of intralipid administration to improve in vitro fertilization (IVF) outcomes. The main finding was that injecting intralipid in women during IVF showed promising results in improving pregnancy and live birth rates. Some background Infertility is faced by many couples and IVF is one way to achieve...
Read MoreComparing the effectiveness and safety of single-dose versus multiple-dose GnRH agonist for luteal-phase support in patients undergoing IVF/ICSI cycles.
In a nutshell This study compared the effectiveness and safety of single-dose (DS) versus multiple-dose (MD) GnRH agonist protocol for luteal phase support in patients undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) cycles. The data showed that the MD protocol was more effective in increasing the live birth and...
Read MorePreparing the uterus for frozen embryo transfer
In a nutshell This study compared two medication protocols to prepare the uterus for frozen embryo transfer (FET). It found that down-regulation ovulation-induction (DROI) led to higher pregnancy rates than a modified natural cycle (mNC). Some background In vitro fertilization (IVF) is an infertility technique in which eggs are collected and...
Read MoreCan a dual trigger shot improve IVF birth rates?
In a nutshell This study looked at whether using two hormone injections to trigger ovulation can improve birth rates from assisted reproductive technology (ART) when all embryos are frozen. It found that cycles with trigger injections of both human chorionic gonadotropin (hCG; Pregnyl) and GnRH agonist (Decapeptyl) had higher birth rates. Some...
Read MoreDoes ICSI benefit couples where men have normal sperm quality?
In a nutshell This trial compared intracytoplasmic sperm injection (ICSI) to conventional in vitro fertilization (IVF) for couples where men have normal sperm quality. It found there was no clear benefit to ICSI over IVF for these couples. Some background IVF is an infertility treatment in which the woman’s ovaries are stimulated to produce...
Read MoreCan an ovulatory cycle improve the pregnancy outcomes of women undergoing frozen embryo transfer?
In a nutshell This review compared pregnancy outcomes following two methods of preparing the uterus for a frozen embryo transfer (FET). It found that natural cycle FET led to fewer pregnancy complications than artificial cycle FET. Some background Frozen embryo transfer (FET) is a common infertility treatment is related to in vitro fertilization...
Read MoreHow does the uterine lining thickness affect pregnancy in each IVF protocol?
In a nutshell This study compared how the thickness of the uterine lining affected outcomes from two protocols for in vitro fertilization (IVF). It found that the GnRH antagonist protocol had better outcomes when the lining was of medium thickness. The long GnRH agonist protocol had better outcomes when there was a thick lining. Some background IVF is...
Read MoreDoes genetic testing improve birth rate?
In a nutshell This review looked at whether genetic testing improved the birth rate from in vitro fertilization (IVF). It found that testing improved birth rates for women over age 35. Some background IVF is a common infertility treatment in which eggs are stimulated and collected, and fertilized embryos implanted back in the uterus. When IVF embryos...
Read MoreComparing IVF protocols and genetic testing outcomes
In a nutshell This study looked at two protocols for in vitro fertilization (IVF) using different timing of medications to suppress the body’s own hormones. It found that patients using a long-acting protocol had fewer embryos with unusual chromosomes (genetic material). Some background Women are born with most of their oocytes (eggs) already...
Read MoreDoes controlled ovarian syndrome alter the vaginal and endometrial microbiota?
In a nutshell This study investigated if controlled ovarian stimulation (COS) and progesterone (P) supplementation affects the microbiota (microorganisms found in the human body) of the vagina and uterus (womb). They found that COS alters the vaginal and uterine microbiota (VUM). Some background The rate of infertility is increasing worldwide. Many...
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