In a nutshell This phase 3 trial will investigate the effectiveness of cemiplimab (Libtayo) and ipilimumab (Yervoy) in combination with platinum-based chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). The main outcome will be response to treatment and survival without cancer growing or spreading. The...
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Looking for participants to test a new treatment combination for advanced colorectal cancer
In a nutshell This trial is examining the effectiveness and safety of treatment with nivolumab (Opdivo) and relatlimab in patients with advanced colorectal cancer. The main outcome to be measured will be tumor response to the treatment. This trial is being conducted in Maryland, US. The details Colorectal cancer is the third most common cancer in the...
Read MoreLooking for patients with lung cancer to trial a new treatment combination
In a nutshell This phase 3 trial will investigate the safety and effectiveness of pembrolizumab (Keytruda) and chemotherapy with or without canakinumab (Ilaris) in non-small cell lung cancer (NSCLC). The main outcomes will be side effects and survival rates. The details Non-small cell lung cancer (NSCLC) is the most common form of...
Read MoreLooking for patients with early-stage breast cancer to test a combination treatment
In a nutshell This phase 3 trial will investigate the effectiveness of pembrolizumab (Keytruda) in combination with pre-surgery chemotherapy and after-surgery hormonal therapy in patients with high-risk early-stage breast cancer (BC). The main outcomes to be measured will be the response to treatment and survival. The details...
Read MoreLooking for patients with relapse/unresponsive lymphoma to test a treatment combination
In a nutshell This study is evaluating the best dose and side effects of mogamulizumab (Poteligeo) plus pembrolizumab (Keytruda) for relapsed or unresponsive lymphoma. The main outcomes to be measured will be the best dose and side effects of treatment, as well as survival without the tumor growing. This study is being conducted in Sacramento,...
Read MoreLooking for children and young adults with Hodgkin lymphoma to test a new treatment.
In a nutshell This trial is examining the safety and effectiveness of pembrolizumab (Keytruda) in the treatment of children and young adults with classical Hodgkin lymphoma (HL). The main outcome to be measured will be a response to treatment. This trial is recruiting in the Republic of Korea and the United States. The details...
Read MoreLooking for patients with colorectal cancer to test a new drug
In a nutshell This phase 2 trial will investigate the safety and effectiveness of tisotumab vedotin (TTV) for the treatment of solid tumors. The main outcome will be the response rate to treatment. This trial will take place in the United States, France, and Italy. The details Colorectal cancer (CRC) is caused by excessive cell growth...
Read MoreLooking for patients with lung cancer to test a new drug
In a nutshell This phase 2 trial will investigate the safety and effectiveness of tisotumab vedotin (TTV) for the treatment of solid tumors. The main outcome will be the response rate to treatment. This trial will take place in the United States, France, and Italy. The details Non-small cell lung cancer (NSCLC) is caused by excessive cell growth in...
Read MoreLooking for participants with metastatic colorectal cancer to try a new treatment combination
In a nutshell This trial is comparing the effectiveness and toxicity of ABT-165 or bevacizumab (Avastin) plus FOLFIRI (irinotecan, leucovorin, fluorouracil) chemotherapy in patients with metastatic (spread to other parts of the body) colorectal cancer. The main outcome to be measured will be tumor response and survival without cancer...
Read MoreLooking for elderly patients with chronic lymphocytic leukemia to test a treatment combination
In a nutshell This trial is examining the effectiveness of ibrutinib and obinutuzumab with or without venetoclax in the treatment of older patients with chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in the United States. The details Patients with CLL are often...
Read MoreLooking for patients with relapsed or unresponsive lymphoma to test a cell therapy
In a nutshell This phase 1 trial is investigating the effectiveness and safety of a new T-cell therapy for relapsed or unresponsive lymphoma. The main outcome to be measured will be the side effects of treatment and long-term survival. This study is being conducted in Chapel Hill, North Carolina, United States. The details In cancer therapy,...
Read MoreLooking for patients with relapsed or unresponsive mantle cell lymphoma to test a new treatment
In a nutshell This phase 2 trial is evaluating the safety and effectiveness of a new targeted therapy for relapsed or unresponsive mantle cell lymphoma (MCL). The main outcome to be measured is the overall response rate to treatment. The details Ibrutinib (Imbruvica) is a commonly used therapy for patients with relapsed or refractory MCL. This...
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