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Searching for patients with solid tumors with abnormal genetic changes to trial an experimental medication

Searching for patients with solid tumors with abnormal genetic changes to trial an experimental medication

Posted by on Apr 30, 2021 in Lung cancer | 0 comments

In a nutshell This study is searching for participants with advanced solid tumors including lung cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US. The details Some cancers grow as a...

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Searching for patients with extensive-stage small cell lung cancer to trial a combination treatment.

Searching for patients with extensive-stage small cell lung cancer to trial a combination treatment.

Posted by on Mar 13, 2021 in Lung cancer | 0 comments

In a nutshell This trial is looking to trial a treatment combination of olaparib (Lynparza), durvalumab (Imfinzi), radiation therapy (RT), and chemotherapy (CT) to treat patients with extensive-stage (ES) small-cell lung cancer (SCLC). The main outcomes to be measured are side effects and survival. This trial is being carried out in Texas,...

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Looking for patients with relapsed or refractory multiple myeloma to trial a treatment combination

Looking for patients with relapsed or refractory multiple myeloma to trial a treatment combination

Posted by on Jan 28, 2021 in Multiple Myeloma | 0 comments

In a nutshell This trial is aiming to examine the effectiveness of combination therapy with venetoclax (Venclexta), daratumumab (Darzalex), and dexamethasone (Ozurdex) with or without bortezomib (Velcade) for unresponsive or relapsed multiple myeloma (MM). The main outcome that is to be measured is the response rate, time to response,...

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Searching for patients with triple-negative breast cancer to test an immunotherapy combination

Searching for patients with triple-negative breast cancer to test an immunotherapy combination

Posted by on Nov 22, 2020 in Breast cancer | 0 comments

In a nutshell This study will investigate the safety and effectiveness of tiragolumab combined with atezolizumab (Tecentriq) and chemotherapy to treat triple-negative breast cancer (TNBC).  The main outcome will be the occurrence of side effects and the objective response rate (ORR).  The details Breast cancer (BC) is the most...

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Searching for patients with EGFR-positive advanced tumors to trial an experimental treatment.

Searching for patients with EGFR-positive advanced tumors to trial an experimental treatment.

Posted by on Nov 22, 2020 in Colorectal cancer | 0 comments

In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced solid...

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Searching for patients with metastatic triple negative breast cancer to trial a cancer vaccine

Searching for patients with metastatic triple negative breast cancer to trial a cancer vaccine

Posted by on Nov 9, 2020 in Breast cancer | 0 comments

In a nutshell This study is looking to trial the addition of a new form of vaccine called a neoantigen vaccine in combination with nab–paclitaxel (Abraxane), duvalumab (Imfinzi), and tremelimumab (CP-675,206), in patients with metastatic triple-negative breast cancer (mTNBC). The main outcome that will be measured is survival without the...

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Searching for patients with advanced non-small cell lung cancer to trial a radiation treatment

Searching for patients with advanced non-small cell lung cancer to trial a radiation treatment

Posted by on Nov 8, 2020 in Lung cancer | 0 comments

In a nutshell This trial is looking at the effectiveness of Quad Shot (QS) radiation therapy (RT) to relieve symptoms in patients with advanced non-small-cell lung cancer (NSCLC). The main outcome that is to be measured is the occurrence of side effects over the course of 3-months. This trial is being carried out in New Jersey and New York,...

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Searching for patients with stage III non-small cell lung cancer to trial a biological treatment.

Searching for patients with stage III non-small cell lung cancer to trial a biological treatment.

Posted by on Sep 6, 2020 in Lung cancer | 0 comments

In a nutshell This trial is aiming to examine the effectiveness and safety of atezolizumab (Tecentriq) and tiragolumab compared to durvalumab (Imfinzi) in stage III non-small-cell lung cancer (NSCLC) that cannot be surgically removed and has previously been treated with concurrent (at the same time) platinum-based chemoradiation therapy (CRT)....

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Looking for patients with newly-diagnosed multiple myeloma to trial a treatment combination

Looking for patients with newly-diagnosed multiple myeloma to trial a treatment combination

Posted by on Aug 30, 2020 in Multiple Myeloma | 0 comments

In a nutshell This study is being carried out to examine whether KRD including carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (Decadron) with or without daratumumab (Darzalex) is safe and effective in the treatment of multiple myeloma (MM). The main outcome to be measured is the measurable residual...

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Looking for patients with metastatic non-small cell lung cancer to trial a biological treatment combination

Looking for patients with metastatic non-small cell lung cancer to trial a biological treatment combination

Posted by on Aug 30, 2020 in Lung cancer | 0 comments

In a nutshell This trial is being carried out to assess the effectiveness of atezolizumab (Tecentriq) in combination with cabozantinib (Cabometyx) versus docetaxel (Taxotere) in patients with metastatic non-small cell lung cancer (NSCLC) which has previously been treated with immunotherapy and platinum-based chemotherapy....

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Looking for patients with metastatic lung cancer to trial a treatment combination

Looking for patients with metastatic lung cancer to trial a treatment combination

Posted by on Aug 30, 2020 in Lung cancer | 0 comments

In a nutshell This trial is being carried out to assess whether osimertinib (Tagrisso) should be used alone or with chemotherapy for lung cancer and abnormalities (mutations) in the EGFR gene. The main outcome that will be measured in this trial is survival without progression of the disease. This trial will take place in New Jersey and New...

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