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Looking for patients with relapsed multiple myeloma to test a biological drug and immune cell vaccine

Posted by on Jul 31, 2019 in Multiple Myeloma | 0 comments

In a nutshell This trial is investigating the effectiveness and side effects of nivolumab (Opdivo) with a dendritic cell vaccine for patients with multiple myeloma (MM). The main outcome of this study would be to see the number of patients that develop an allergic reaction to the treatment. This study is recruiting in Boston, MA, United...

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Searching patients with relapsed or unresponsive cancer to test a new medication

Posted by on Jul 31, 2019 in Lung cancer | 0 comments

In a nutshell This phase 1b/2 trial will investigate the safety of RMC-4630 and cobimetinib (Cotellic) in relapsed or unresponsive solid tumors.  The main outcomes will be the number of side effects and the overall response rate. This trial is recruiting in a number of US states.  The details Relapsed/refractory (R/R) cancer is a term for...

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Looking for participants with advanced colorectal cancer to test a new combined treatment

Posted by on Jul 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of liposomal irinotecan (LI; Onivyde) and rucaparib (Rubraca) in treating patients with advanced colorectal cancer. The main outcome to be measured will be the toxicity and tumor response to the treatment. This trial is being conducted in Arizona, Georgia, Minnesota, and Utah, US. The...

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Looking for participants with advanced cancer to test a new therapy

Posted by on Jul 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This trial is examining the effectiveness and toxicity of COTI-2 treatment in patients with advanced cancer. The main outcomes to be measured will be cancer response to the treatment and number of side effects. This study is being conducted in Texas, US. The details Cancer resistance to therapy affects successful cancer treatment. The...

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Looking for patients with breast cancer to trial a new chemotherapy drug combined with targeted therapy

Posted by on Jul 24, 2019 in Breast cancer | 0 comments

In a nutshell This phase 2 trial will investigate the effects of tesetaxel combined with targeted therapy drugs in advanced breast cancer (BC).  The main outcomes will be the overall response rate (ORR) and progression-free survival (PFS). This trial is recruiting in Boston, MA and East Setauket, NY.   The details Some...

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Searching for patients with lung cancer to trial a combination of immunotherapy and chemoradiation

Posted by on Jul 24, 2019 in Lung cancer | 0 comments

In a nutshell This trial aims to investigate the safety and effectiveness of durvalumab (Imfinzi) combined with chemotherapy and radiation in patients with advanced lung tumors. The main outcome that will be measured is if there are any side effects and survival without signs of disease. The details Duravalumab is an anti-cancer...

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Looking for patients with inoperable metastatic colorectal cancer to test a new immunotherapy

Posted by on Jul 5, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of a new immunotherapy in the treatment of patients with advanced colorectal cancer (CRC). The main outcome to be measured will be tumor response to the treatment. This study is being conducted in Texas, USA.   The details CRC is the third most common cancer worldwide. The 5-year...

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