In a nutshell The authors aimed to compare safety of a combination therapy over a single therapy in advanced melanoma patients. Some background In the advanced stage of melanoma (stage III/IV), cancer spreads from the skin to other parts of the body. In the majority of advanced melanoma patients, BRAF genes are mutated (permanently...
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In a nutshell This study compared quality of life among advanced melanoma patients receiving either trametinib (Mekinist) or chemotherapy. Some background Until recently, chemotherapy was the treatment of choice in the treatment of wide spread melanoma. Since the identification of commonly occurring genetic mutations in melanoma tumors, several...
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In a nutshell This study examined the most accurate predictor of survival in patients with metastatic melanoma being treated with bevacizumab (Avastin). Some background Since melanomas are highly dependent on the formation of new blood vessels, bevacizumab (Avastin), a drug which blocks new blood vessel formation, is often used in their treatment....
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