In a nutshell This study compared whether radiotherapy (RT) was more effective when combined with hormone therapy or brachytherapy (BT) for patients with localized prostate cancer (PC). The authors found that patients who received hormone therapy and RT survived for longer. Some background External beam radiotherapy (EBRT) focuses beams of...
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In a nutshell The study investigated the use of relugolix (Relumina), a hormonal therapy drug, in addition to radiotherapy (RT), in managing prostate cancer. The study found that relugolix was effective in reducing androgen (male sex hormones such as testosterone) levels and well tolerated in these patients. Some background Prostate...
Read MoreIn a nutshell This study aimed to investigate the best timing of treatment verification imaging used in radiation therapy for patients with prostate cancer. This study found that patients undergoing daily imaging had less risk of their cancer returning and had reduced rectal side-effects. Some background One main treatment option for prostate cancer...
Read MoreIn a nutshell This study compared the side effects of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) on erectile and sexual function. Researchers reported similar effects of EBRT and H-EBRT on erectile and sexual function up to 3 years after treatment. Some background Radiation therapy is a common treatment for localized...
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In a nutshell This study compared different external beam radiation therapy (EBRT) approaches for localized prostate cancer. Authors reported high effectiveness with higher doses of radiation therapy, particularly when hormone therapy was added to treatment. However, these combinations were also associated with the highest rate of side effects. Some...
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In a nutshell The authors aimed to determine whether hormone therapy had an effect on biochemical failure and cancer spread in prostate cancer patients undergoing radiation therapy. Some background Intermediate-risk prostate cancer is cancer that requires active treatment due to growth through and/or out of the prostate. It can be treated...
Read MoreIn a nutshell This review analyzed recent publications investigating the late intestinal adverse effects following radiotherapy treatments. Some background Radiotherapy is frequently used in the treatment of prostate cancer. Although radiation techniques have improved over recent years, radiotherapy still commonly causes intestinal adverse events....
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This review article describes clinical evidence of the benefits and risks of a treatment combined of a short course of hormonal therapy (termed ‘androgen deprivation therapy’, ADT) and radiation given in escalated doses. Patients involved were those with localized prostate cancer but higher Gleason score or prostate-specific antigen (PSA)...
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