In a nutshell This study compared fertility medications for intrauterine insemination (IUI) for women with diminished ovarian reserve (DOR). It found that letrozole (Femara) and clomiphene citrate (Clomid) tablets gave similar results to injected gonadotropins (Gonal-F). Some background DOR is a condition in which few ovarian follicles (which...
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In a nutshell This study investigated if the long-term development of children is affected by the type of embryo transfer (ET). They found that there were similar outcomes with fresh (fr) and frozen (fz) ET. Some background Assisted reproduction (AR) is used to treat infertility. It has become more common in recent years. There are a number of...
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In a nutshell This study investigated factors that affect the fertility outcomes with intrauterine insemination (IUI) after controlled ovarian stimulation (COS). They found that clinical pregnancy (CPR) and live birth rates (LBR) were associated with female age. Some background Assisted reproduction (AR) is used to treat infertility. There are a...
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In a nutshell This study investigated if intrauterine insemination (IUI) is associated with improved pregnancy outcomes in women with a low ovarian reserve. They found that pregnancy outcomes after IUI were similar in women with normal and low ovarian reserve. Some background Infertility can have many causes. One cause is a low ovarian...
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In a nutshell This analysis compared gonadotropin hormone treatment versus oral drugs for use with intrauterine insemination (IUI). This study found that hormone treatment increased pregnancy rates but also had a higher risk of twins. Some background Ovarian stimulation with IUI is a standard initial treatment for infertility. Ovarian...
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In a nutshell This paper studied the perinatal effects on babies conceived through intrauterine insemination. Some background Intrauterine insemination is a fertility treatment where fast moving sperm are placed into the woman's womb close to the time when the egg is released from the ovary in the middle of the monthly cycle. Artificial...
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In a nutshell This review explored the use and benefits of progesterone supplementation in women undergoing ovulation induction and intrauterine insemination. Some background The successful implantation of a fertilized egg into the uterus is only possible if the uterus is receptive. This requires progesterone, a hormone released during the luteal...
Read MoreIn a nutshell This study compared pregnancy outcomes in patients who received one of two ovulation stimulating drugs – tamoxifen or clomiphene citrate. Some background Treatment for female infertility usually begins with drugs that stimulate ovulation. By producing more eggs, there is a higher likelihood of a successful...
Read MoreIn a nutshell This article reviewed current data regarding pregnancy outcomes in women with endometriosis treated with a gonadotropin-releasing hormone (GnRH) analog before in-vitro fertilization (IVF). Some background Endometriosis is a condition in which cells of the inner-most layer of the uterus can be found in other organs (most commonly the...
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In a nutshell This study looked at in-vitro fertilization (IVF) outcomes in couples with unexplained infertility. Two egg fertilization techniques were compared: intracytoplasmatic sperm injection versus conventional insemination. Some background IVF involves the artificial joining of eggs and sperm in a laboratory dish. This is typically achieved...
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In a nutshell This article looked at the different surgical options available for women who have trouble conceiving due to fallopian tube dysfunction. Some background The fallopian tubes (FT) connect the ovaries to the uterus. For a normal pregnancy to occur, an egg released by the ovary needs to travel through its...
Read MoreIn a nutshell This article outlines the current methods available to improve in vitro fertilization (IVF) success rates in women over 35 years old. The authors discuss the outcomes of a single embryo transfer of an embryo that has been genetically selected. Some background IVF involves the artificial matching of a...
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