In a nutshell This study evaluated how long estrogen should be used during artificial cycle frozen embryo transfer (FET). It found that stopping estrogen at 6 weeks of pregnancy reduced miscarriages compared to continuing to 12 weeks. Stopping at 6 weeks also led to fewer pregnancy complications. Some background FET is a common infertility...
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In a nutshell This study looked at the overall birth rate using multiple in vitro fertilization (IVF) cycles and freezing all embryos. It found that when using multiple cycles, the birth rate varied widely depending on the woman’s age and cause of infertility. Some background In vitro fertilization (IVF) is an infertility technique in which the...
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In a nutshell This study compared two methods of preparing for frozen embryo transfer (FET) for women who do not ovulate regularly. It found that letrozole (Femara) led to fewer miscarriages and higher birth rates than hormone replacement therapy (HRT). Some background FET is an increasingly common infertility treatment. FET uses additional embryos...
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In a nutshell This review looked at different hormonal methods to prepare the uterus for a frozen embryo transfer (FET). It found that cycles with ovulation led to better outcomes than an artificial cycle. Some background FET is an infertility treatment in which a frozen embryo is transferred into the uterus. The lining of the uterus needs to be...
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In a nutshell This review looked at whether luteal phase support (LPS) using progesterone benefitted natural cycle frozen embryo transfers (FETs). It found that FETs with progesterone support had higher pregnancy and birth rates. Some background Frozen embryo transfer (FET) is an increasingly common infertility treatment. This technique transfers an...
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In a nutshell This review looked at the effect of endometriosis surgery before in vitro fertilization (IVF). It found that surgery led to better pregnancy outcomes for patients with severe endometriosis. Some background Endometriosis is a condition in which cells from the lining of the uterus grow on the ovaries, Fallopian tubes, or other places...
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In a nutshell This analysis looked at which factors influence the risk of miscarriage for women with polycystic ovarian syndrome (PCOS) who were undergoing infertility treatment. It found that being overweight and insulin resistance can increase miscarriage risk in these patients. Some background Metabolism, hormones, and fertility are closely...
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In a nutshell This review compared medication protocols for in vitro fertilization (IVF) for women with a poor ovarian response (POR). It found that delayed start antagonist (DSA) protocol may improve IVF outcomes for patients with POR. Some background The infertility treatment IVF is a method to collect oocytes (eggs), fertilize them artificially,...
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In a nutshell This review compared starting ovarian stimulation (OS) for egg collection at the conventional time early in the menstrual cycle, to starting it in the luteal phase, late in the cycle. It found that both timelines led to successful egg collection. Using two collections in one cycle may improve outcomes for patients with a poor response to...
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In a nutshell This study compared natural cycle (NC) or hormone replacement cycle (HRC) in terms of fertility outcomes in women undergoing frozen embryo transfer (fzET). They found that fertility outcomes were similar with NC or HRC. Some background Assisted reproductive technology (ART) is used to treat infertility. ART includes...
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In a nutshell This study investigated if dual (intramuscular and vaginal) progesterone (PG) administration improves fertility outcomes in women undergoing in vitro fertilization (IVF). They found that dual PG led to similar fertility outcomes as a single intramuscular PG administration. Some background Assisted reproduction...
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In a nutshell This analysis looked at the effects of metformin (Glucophage) for women with polycystic ovarian syndrome (PCOS) who are undergoing in vitro fertilization (IVF). It found that metformin lowers the risk of ovarian hyperstimulation syndrome (OHSS), and may increase pregnancy rates for those who are overweight. Some background PCOS is a...
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