In a nutshell This study investigated the effect of sperm morphology (SM; size and shape of sperm) on fertility outcomes in couples undergoing fertility treatment. They found that abnormal SM is associated with poorer fertility outcomes. Some background Male infertility (MI) is a common cause of infertility. Reduced sperm...
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In a nutshell This study investigated sperm selection techniques in couples undergoing assisted reproduction (AR). They found that the choice of sperm selection techniques should be based on female age. Some background Assisted reproduction (AR) is used to help infertile couples. Male infertility (MI) is the cause in 30-50% of cases. MI can...
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In a nutshell This study looked at mini-incision micro-dissection testicular sperm extraction, a modified surgery to collect sperm. It found that this was a useful procedure for men who do not produce enough sperm and that it may be less invasive than other surgeries. Some background Non-obstructive azoospermia (NOA) is a condition in which a man...
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In a nutshell This study compared natural cycle versus hormone replacement in vitro fertilization (IVF) for infertile women with regular menstrual cycles. It found that natural cycle IVF led to higher birth rates. Some background Frozen embryo IVF is a treatment for infertility in which eggs are removed from the woman and fertilized. The embryo(s) are...
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In a nutshell This study investigated if endometrial thickness (EMT) is associated with neonatal outcomes after fresh embryo transfer (Fr-ET). They found that a low EMT was associated with the risk of small-for-gestational-age (SGA) infants. Some background Assisted reproduction (AR) is used to treat infertility. Procedures like in vitro...
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In a nutshell This study looked at whether embryo transfer on day 3 or day 4 to 5 was better for patients undergoing IVF (in vitro fertilization). This study found that day 3 transfer led to better outcomes compared to transfer on a later day. Some background In vitro fertilization (IVF) is an infertility treatment in which eggs are removed from a...
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In a nutshell This study looked at whether injecting HCG hormone into the womb before embryo transfer improved pregnancy rates. This study concluded that HCG improved pregnancy rates for women with a history of unsuccessful implantation. Some background One cause of infertility is poor implantation of an embryo in the uterus. This occurs when the...
Read MoreIn a nutshell The aim of this phase 4 trial is to assess if a single dose of a gonadotrophin-releasing hormone (GnRH) agonist enhances implantation during in vitro fertilization (IVF). The main outcome to be measured is the rate of live births. This study is being conducted in New Jersey, in the United States. The details In very early pregnancy,...
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In a nutshell This study investigated whether artificial activation of the female egg during intracytoplasmic sperm injection treatment improves fertilization and pregnancy rates. Some background Intracytoplasmic sperm injection (ICSI) is a method of fertilization often performed as part of in-vitro fertilization (IVF). ICSI includes...
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