In a nutshell This study investigated the impact of whole breast radiation therapy (WBRT) and accelerated partial breast irradiation (APBI) on the severity of post-treatment side effects and quality of life. This study concluded that both forms of radiation therapy (RT) show similar survival benefits and similar quality of life in early-stage breast...
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In a nutshell This study examined the effects of a combination of two treatments, low-dose capecitabine (Xeloda) and docetaxel (Taxotere), versus docetaxel alone in patients with metastatic, HER2-negative breast cancer. The study concluded that combination treatment improved time to disease progression. Some background...
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In a nutshell This study investigated sentinel lymph node biopsy (SLNB) as a procedure to determine the staging of breast cancer in patients who had received neoadjuvant chemotherapy (chemotherapy given before surgery). The authors concluded that SLNB was suitable for staging of the cancer in patients with breast cancer that had not spread to the...
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In a nutshell This study examined the predictive value of circulating tumor cells (CTCs) during docetaxel (Taxotere) treatment for metastatic castration-resistant prostate cancer (mCRPC). Researchers reported a strong association between CTCs and treatment response to docetaxel. Some background Hormone therapy is the standard of care for advanced...
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In a nutshell This study investigated the benefits of chemotherapy in colorectal cancer patients with inoperable liver metastasis (the cancer has spread to the liver). Researchers reported that chemotherapy increases survival in colorectal patients with inoperable liver metastasis. Some background Only 10-20% of colorectal patients with...
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In a nutshell This review analyzed platinum-based drugs in the treatment of advanced castration-resistant prostate cancer. While platinum-based drugs were often associated with various side effects, researchers reported moderate to good treatment effectivity in managing advanced prostate cancer. Some background Hormone therapy is the standard...
Read MoreIn a nutshell This study investigated the association between malnutrition caused by pre-surgery chemotherapy and radiation (CRT) and rectal cancer treatment tolerance and anastomotic leakage (AL; leakage of intestinal fluids). Researchers reported that malnutrition related to CRT is associated with treatment tolerance and AL. Some background CRT...
Read MoreIn a nutshell This review examined intermittent and continuous docetaxel (Taxotere) treatment for metastatic castration-resistant prostate cancer (mCRPC). Researchers concluded that intermittent docetaxel treatment can be a feasible treatment option in the management of mCRPC. Some background Chemotherapy with docetaxel is often the first-line...
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In a nutshell This review evaluated first-line treatments for metastatic castration-resistant prostate cancer (mCRPC). Authors recommend chemotherapy with docetaxel (Taxotere) for mCRPC with high tumor burden or at high risk of rapid progression. Alternative hormonal therapy or chemotherapy may be effective in other cases. Some background...
Read MoreIn a nutshell This study investigated the effectiveness and safety of neratinib treatment in patients with early-stage HER2+ breast cancer. The study concluded that neratinib significantly improved 2-year invasive disease-free survival in women with HER2+ breast cancer. Some background HER2 positive (HER2+) breast cancer is dependent on the...
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In a nutshell This study looked at the effectiveness of a new granisetron (Sustol) formulation for the treatment of nausea and vomiting during breast cancer treatment. The study concluded that the new formulation effectively prevented nausea and vomiting over 4 chemotherapy cycles in breast cancer patients. Some background A known side effect of...
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In a nutshell This study investigated the appropriate waiting time to surgery after radiation and chemotherapy in rectal cancer patients. Researchers suggested that 56 days is the optimal waiting time for surgery after completion of radiation or chemotherapy. Some background Chemotherapy and radiation prior to surgery to remove rectal cancer has...
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