In a nutshell This study aimed to investigate if allogeneic hematopoietic cell transplantation is effective in patients who have progressed from chronic lymphocytic leukemia to Richter syndrome. This study concluded that allogeneic hematopoietic cell transplant is effective for these patients if they had an objective response before...
Read MoreIn a nutshell This study investigated the effectiveness of stem cell transplantation in follicular lymphoma patients who experienced early treatment failure after frontline chemoimmunotherapy. This study concluded that transplants using the patient's own stem cells or those from a matched sibling donor lead to better survival outcomes in these...
Read MoreIn a nutshell This study aimed to compare two conditioning treatment regimens for adult patients with Ph-negative acute lymphoblastic leukemia treated with stem cell transplant. This study concluded that the regimen that combined etoposide (Etopophos) and total body irradiation was more effective than the regimen that combined cyclophosphamide (Neosar)...
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In a nutshell This study aimed to investigate the use of stem cell transplant with a chemotherapy treatment regime in patients with acute myeloid leukemia. This study concluded that this regime is safe and effective in patients that receive stem cell transplants from a haploidentical (half or partially matched) donor. Some background The use of...
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In a nutshell This study aimed to investigate the prevalence of metabolic syndrome in adult survivors of childhood acute leukemia. This study also aimed to determine the effect of different therapies on the occurrence of metabolic syndrome in these patients. This study concluded that metabolic syndrome is frequent among childhood AL survivors, regardless...
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In a nutshell This study aimed to evaluate the effect of stem cell source on haploidentical transplantation with post-transplantation cyclophosphamide (a chemotherapy) in patients with acute leukemia. This study concluded that the use of peripheral blood stem cells increases the risk of side effects for these patients. Some background Patients...
Read MoreIn a nutshell This study aimed to compare myeloablative transplant and a sequential approach treatment in patients with relapsed or refractory acute myeloid leukemia. This study concluded that both treatments had similar outcomes for these patients. Some background Allogeneic hematopoietic stem cell transplantation (HSCT) is the only...
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In a nutshell This study aimed to investigate the effect of early tapering of immunosuppressive agents after stem cell transplants in patients with acute myeloid leukemia. This study concluded that early tapering of immunosuppressive agents after stem fell transplants in these patients can improve survival. Some background Allogeneic...
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In a nutshell This study aimed to investigate if body mass index can impact outcomes of children with acute leukemia undergoing stem cell transplantation. This study concluded that being underweight at the time of transplant is associated with an increased risk of acute graft versus host disease in these patients. Some background Body mass...
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In a nutshell This study aimed to investigate if the motor skills of pre-school children with acute leukemia were affected after treatment with hematopoietic stem cell transplant. This study concluded that treatment with hematopoietic stem cell transplant can have a negative impact on this group of patients. Some background Childhood acute...
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In a nutshell This report aimed to update recommendations from 2014 about primary prevention of invasive fungal infections in patients with hematological malignancies (blood cancers). There were several updates to the recommendations. Some background Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are hematological...
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In a nutshell This study aimed to investigate if donor age and kinship affected the outcome of haploidentical hematopoietic cell transplantation for acute leukemia patients. This study concluded that both factors can affect the outcome for these patients. Some background Haploidentical hematopoietic cell transplantation (halpo-HCT)...
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