In a nutshell This study investigated the health-related quality of life (HRQoL) for patients with relapsed/refractory (RR) multiple myeloma (MM) patients treated with D-Vd (daratumumab, bortezomib, and dexamethasone) compared to Vd (bortezomid and dexamethasone). The study showed that HRQoL did not decrease for 8 therapy cycles and long-term...
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Quality of life during treatment with PVd for multiple myeloma
In a nutshell This trial looked at the quality of life (QOL) of patients receiving PVd (pomalidomide, bortezomib, dexamethasone) for multiple myeloma which has returned after previous treatment. This study showed that adding pomalidomide (Pomalyst) to the Vd regimen (bortezomib, dexamethasone) did not decrease patients' QOL. Some background...
Read MoreDoes age influence the safety and effectiveness of stem cell treatment for patients with multiple myeloma?
In a nutshell This study examined the safety and effectiveness of stem cell transplantation (SCT) in elderly patients with multiple myeloma (MM) aged 65 or older compared to younger patients. The authors concluded that SCT was equally as safe and effective for patients in both age groups. Some background Multiple myeloma is a complex type of...
Read MoreCan bortezomib be safely injected in the comfort of patients own home?
In a nutshell This article investigated the safety and effectiveness of subcutaneous (under the skin) injection at home of bortezomib (Velcade) in elderly and frail patients on the bortezomib–melphalan–prednisone (VMP) regimen. The authors concluded that domestic injection of bortezomib is safe and can...
Read MoreStem cell transplantation and lenalidomide improves survival of patients with multiple myeloma
In a nutshell This article investigated the safety and effectiveness of high-dose therapy with autologous stem cell transplantation (HDT-ASCT) and maintenance treatment (treatment meant to keep cancer from coming back) with lenalidomide (Revlimid) for patients with multiple myeloma. The authors concluded that this therapy is safe...
Read MoreWhat is the benefit of adding ixazomib to lenalidomide and dexamethasone for relapsing/refractory multiple myeloma?
In a nutshell This study investigated the effects of adding ixazomib (Ninlaro) to lenalidomide (Revlimid) and dexamethasone (Dexasone) for patients with unresponsive multiple myeloma. The main finding was that patients receiving ixazomib plus lenalidomide and dexamethasone survived longer without worsening of cancer (progression-free...
Read MoreCarfilzomib – once weekly or twice weekly to treat unresponsive multiple myeloma?
In a nutshell This study investigated the safety and effectiveness of two different doses of carfilzomib (Kyprolis) for patients with relapsed or refractory multiple myeloma. This study concluded that once weekly carfilzomib is safe and more effective than the twice weekly dose for these patients. Some background Multiple myeloma is a type of cancer...
Read MoreIs rituximab/bendamustine safer and more effective than R-CHOP in patients with grade 3A follicular lymphoma?
In a nutshell This study investigated the effectiveness and safety of the R-B (rituximab, bendamustine) regimen versus the R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) regimen in patients with grade 3A follicular lymphoma (FL3A). This study concluded that R-B is better tolerated and more effective than R-CHOP, making it a...
Read MoreThe effectiveness of lenalidomide to treat patients with relapsed or refractory mantle cell lymphoma
In a nutshell This study compared lenalidomide (Revlimid) with the doctor’s choice of medication in patients with relapsed or refractory mantle cell lymphoma. The study concluded that lenalidomide significantly improved outcomes for patients with mantle cell lymphoma. Some background Mantle cell lymphoma (MCL) is a type of non-Hodgkin...
Read MoreAsk the Expert: Any Updates on the Use of the New Immuno-Drugs for Maintenance in Myeloma?
Video information: After receiving a successful treatment, it’s recommended that patients turn to maintenance therapy to help safeguard their quality of life and help control the residual myeloma cells from developing. The landscape for maintenance therapy continues to expand as the potential effects of new immuno-drugs emerge. Listen in as...
Read MoreMyeloma Update From ASCO 2017
Video information: On location at the recent 2017 American Society of Clinical Oncology meeting (ASCO), Dr. Hearn Jay Cho of Mount Sinai Hospital discusses news out of ASCO 2017 and what it means for myeloma patients and care partners. Dr. Cho highlights news out of the meeting, including how experts are manipulating the immune system, precision...
Read MoreThe safety and outcomes of lenalidomide treatment for patients with relapsed or difficult to treat mantle cell lymphoma
In a nutshell This study looked at the use of lenalidomide (Revlimid) treatment for patients with relapsed mantle cell lymphoma. The authors concluded that lenalidomide is generally safe and effective for treating patients with advanced stage relapsed or difficult to treat mantle cell lymphoma. Some background Mantle cell lymphoma (MCL) is an...
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