In a nutshell This clinical study will investigate the use of daily ultrasound for the treatment of rheumatoid arthritis (RA). The main outcome of interest is an improvement in RA disease activity. The trial will take place in Minneapolis, Minnesota, United States. The details Rheumatoid arthritis (RA) is a long-term condition caused...
Read MoreNumber of joints involved-Five or more Posts on Medivizor
A review of treatments for polyarticular juvenile idiopathic arthritis
In a nutshell The authors reviewed current treatment options for the treatment of polyarticular juvenile idiopathic arthritis (pJIA). Some background JIA is the most common form of arthritis in children under the age of 16. In pJIA, more than 6 joints are involved in the first 6 months of the disease. Recent studies have shown that pJIA patients...
Read MoreEffect of certolizumab pegol in rheumatoid arthritis
In a nutshell The authors evaluated the safety and effectiveness of certolizumab pegol (Cimzia) in patients with low to moderate rheumatoid arthritis (RA). Some background In RA, high levels of immune system proteins are generated. This causes inflammation, leading to chronic pain. Disease-modifying antirheumatic drugs...
Read MoreComparing SB2 with infliximab in patients with rheumatoid arthritis
In a nutshell The authors compared the effectiveness and safety of SB2, a biological variant of infliximab (Remicade) — the original biological product, to infliximab itself in patients with moderate to severe rheumatoid arthritis (RA). Some background In RA, high levels of immune system protein are generated...
Read MoreComparing SB4 with etanercept in patients with rheumatoid arthritis
In a nutshell The authors compared the effectiveness and safety of SB4, a biological variant of etanercept (Enbrel), to etanercept alone in patients with rheumatoid arthritis (RA). Some background In RA, high levels of immune system protein are generated, which causes inflammation. This can lead to...
Read MoreMaintenance therapy over dose reduction: which one to choose in RA remission?
In a nutshell The authors analyzed the effect of dose reduction in rheumatoid arthritis patients (RA) in remission (disease recovery). Some background Disease-modifying antirheumatic drugs (DMARDs) are safe and effective treatments in patients with RA. DMARDs can be chemical or biological. The objective of these treatments is to achieve...
Read MoreIdentifying rheumatoid arthritis patients that are suitable for a lower dose of anti-TNF alpha therapy
In a nutshell This study examined whether a combination of clinical and ultrasound assessments could identify rheumatoid arthritis patients suitable for a lower dose of anti-TNF alpha therapy. Some background Anti-TNF alpha therapy (Humira, Enbrel, Remicade and Cimzia) is used to treat patients who have a severe form of rheumatoid...
Read MoreDelayed progression of joint damage with aggressive initial treatment in early rheumatoid arthritis
In a nutshell This study evaluated the frequency of disease remission and the long-term progression of joint damage in patients with early rheumatoid arthritis initially treated with aggressive combination therapy compared to a single anti-rheumatic drug. Some background Rheumatoid arthritis (RA) is a life-long condition characterized by chronic...
Read MoreAggressive versus step-up treatment approach for early rheumatoid arthritis
In a nutshell This clinical trial compared between different approaches for early rheumatoid arthritis treatment. Some background It is recommended for patients who were recently diagnosed with rheumatoid arthritis (RA) to start medical treatment as early as possible in order to reduce disease progression and long-term disability. But what is the...
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