In a nutshell This study compared a combination of pioglitazone (Actos) and exenatide (Byetta) to insulin therapy for poorly controlled type 2 diabetes (T2D). It found that more patients receiving pioglitazone and exenatide achieved blood glucose control compared to those receiving insulin. Some...
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Evaluating the safety of glimepiride for patients with Type 2 diabetes
In a nutshell This study evaluated the side effects in patients with type 2 diabetes (T2D) after treatment with glimepiride (Amaryl). The authors found that while glimepiride lowered mortality, the rate of most side effects was the same as other similar drugs. Some background Treatments for T2D aim to lower blood glucose...
Read MoreLooking for patients with type 2 diabetes to test new treatment BTI320
In a nutshell The aim of this study is the test the effectiveness of new drug BTI320 on blood glucose control in type 2 diabetes (T2D). The main outcome to be measured will be a change in blood glucose 2 hours after meals. This study is being carried out in the United States. The details The number of patients with T2D is constantly on the rise....
Read MoreTreating diabetes: Which drug is safer?
In a nutshell This study compared the risks associated with treatment with a sulphonylurea or metformin (Glucophage) in patients with type 2 diabetes. Some background Type 2 diabetes is a chronic, progressive disease that occurs due to increased resistance to insulin. It can be treated with several drugs. The first-line drug, which is most...
Read MoreUncontrolled diabetes? Another drug might help!
In a nutshell This study evaluated the effectiveness and safety of adding vildagliptin (Galvus, Zomelis, Jalra) to a metformin (Glucophage) and sulfonylurea (Amaryl, DiaBeta) combination in patients with type 2 diabetes. Some background Type 2 diabetes is a chronic progressive disease that occurs due to resistance to insulin. There are several...
Read MoreA comparison between the effects of Sulfonylurea and Metformin on cardiovascular events in patients with type 2 Diabetes Mellitus
In a nutshell The present study compared the effects of therapy with either Metformin or Sulfonylureas (Glyburide, Glipizide) on cardiovascular events (heart attack and stroke) or death in patients with type 2 diabetes mellitus (DM2). The main findings were that treatment with Sulfonylurea was associated with an increased risk of cardiovascular disease...
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