In a nutshell This study looked at the risk of urogenital infections in patients with diabetes taking sodium-glucose co-transporter 2 (SGLT2) inhibitors. It found that SGLT2 inhibitors increase the risk of urogenital infections in women over 50 years of age, especially in the first month of treatment. Some background SGLT 2 inhibitors such...
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Is liraglutide an effective add-on treatment for poorly controlled type 2 diabetes?
In a nutshell This study evaluated whether liraglutide (Victoza) improves diabetic control in patients with difficult to control type 2 diabetes (T2D) and if there were certain factors that influence the effects of liraglutide. It found that patients responded equally well to liraglutide regardless of body mass index (BMI; a measurement of...
Read MoreDo SGLT2 inhibitors reduce heart disease compared to DPP-4 inhibitors?
In a nutshell This study compared the effects on heart disease for SGLT2 inhibitors vs DPP-4 inhibitors in patients with type 2 diabetes (T2D). It found that patients using SGLT2 inhibitor medications had lower rates of heart failure, heart attack, and stroke. Some background T2D is a disorder of high levels of glucose (sugar) in the blood. T2D...
Read MoreIs the off-label use of type-2 diabetes medications in type 1 diabetes causing increased rates of diabetic ketoacidosis?
In a nutshell This study examined the frequency of sodium-glucose cotransporter 2 (SGLT2) inhibitor use in type 1 diabetes (T1D) and the resulting rates of diabetic ketoacidosis (DKA). The study concluded that while the proportion of SGLT2 use in T1D is small, there is a significant associated risk of DKA. Some background There are two...
Read MoreCan dapagliflozin help improve blood magnesium levels in patients with Type 2 diabetes?
In a nutshell This study examined the effects of dapagliflozin (Forxiga) on blood magnesium levels in patients with type 2 diabetes (T2D). The authors concluded that dapagliflozin treatment helped improve blood magnesium levels in these patients. Some background T2D is associated with a number of other health complications. Patients with T2D...
Read MoreDo SGLT2 inhibitors prevent cardiovascular complications in type 2 diabetes?
In a nutshell This study investigated whether SGLT2 (sodium-glucose co-transporter-2) inhibitors reduced the risk of cardiovascular complications in patients with type 2 diabetes. They found that SGLT2 inhibitors were associated with reduced risk of cardiovascular disease and mortality compared to other treatment types. Some background...
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