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Limited or extensive disease-Extensive disease Posts on Medivizor

Does atezolizumab added to chemotherapy improve survival in patients with small-cell lung cancer?

Does atezolizumab added to chemotherapy improve survival in patients with small-cell lung cancer?

Posted by on Mar 5, 2021 in Lung cancer | 0 comments

In a nutshell This article looked at the outcomes of patients with extensive-stage (ES) small cell lung cancer (SCLC) treated with atezolizumab (Tecentriq), carboplatin (CP; Paraplatin), and etoposide (ET; Etopophos). The authors found that the addition of atezolizumab to CP/ET chemotherapy improved the outcomes of these...

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Can immune checkpoint inhibitors be used in the treatment of extensive-stage small cell lung cancer?

Can immune checkpoint inhibitors be used in the treatment of extensive-stage small cell lung cancer?

Posted by on Oct 18, 2020 in Lung cancer | 0 comments

In a nutshell This article looked at the use of immune checkpoint inhibitors (ICIs) in the treatment of extensive-stage (ES) small cell lung cancer (SCLC). The authors found that the addition of atezolizumab (Tecentriq) or durvalumab (Imfinzi) to first-line platinum-based chemotherapy prolongs survival and improves the quality of life...

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Looking for patients with untreated extensive-stage small cell lung cancer to trial a immunotherapy combination

Looking for patients with untreated extensive-stage small cell lung cancer to trial a immunotherapy combination

Posted by on Aug 15, 2020 in Lung cancer | 0 comments

In a nutshell This trial is examining the effectiveness of atezolizumab (Tecentriq) plus carboplatin (Paraplatin) and etoposide (Etopophos) with or without tiragolumab in patients with untreated extensive-stage small-cell lung cancer (ES-SCLC). The main outcomes that will be measured are progression-free survival (PFS) and overall survival...

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Search for patients with relapsed or unresponsive small cell lung cancer to try a treatment combination

Posted by on Jun 29, 2019 in Lung cancer | 0 comments

In a nutshell This study wants to find out how well talazoparib (Talzenna) and temozolomide (Temodal) work for treating patients with small cell lung cancer that has come back after or was unresponsive to initial chemotherapy. The main outcome that will be measured is how long the patients go before the cancer grows. The study is...

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Dalotuzumab in extensive-stage small-cell lung cancer

Posted by on Mar 30, 2015 in Lung cancer | 0 comments

In a nutshell The authors aimed to determine the effects of dalotuzumab in treating small-cell lung cancer when combined with cisplatin and etoposide. Some background Extensive-stage small-cell lung cancer (SCLC – cancer has spread outside of the chest) represents 15% of all lung cancer cases. Though numerous treatments have been used over...

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Chemotherapy combinations in the treatment of patients with extensive small-cell lung cancer

Posted by on Aug 8, 2013 in Lung cancer | 0 comments

In a nutshell This phase III study compared the benefit of three chemotherapy combinations as first line treatment (the first choice of treatment) for extensive disease small-cell lung cancer (ED-SCLC) patients. Topotecan–cisplatin (TP) combination treatment, topotecan–etoposide (TE) combination treatment, and cisplatin-etoposide (PE)...

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