In a nutshell The study compared the effectiveness of letrozole (Femara)/gonadotropin combination to letrozole alone in infertile women with polycystic ovarian syndrome (PCOS). The study found that the combination of letrozole/gonadotropin was more effective than letrozole alone in these women. Some background Polycystic ovarian syndrome or...
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Evaluating the effectiveness of physical exercise programs in breast cancer survivors on health-related quality of life, physical fitness, and body composition
In a nutshell The study evaluated the effectiveness of physical exercise (PE) programs in breast cancer (BC) survivors on health-related quality of life (HRQoL), physical fitness, and body composition. The study concluded that PE programs do have a positive impact on BC survivors’ HRQoL, physical fitness, and body composition. Some background...
Read MoreHow beneficial is a Mediterranean diet and physical activity to females with rheumatoid arthritis?
In a nutshell This study investigated the effect of a Mediterranean diet (MD) intervention with physical activity on rheumatoid arthritis (RA) disease status and the risk of cardiovascular diseases in women. The data showed that a personalized MD plan along with physical activity (PA) may provide benefits to females with RA. Some background RA is a...
Read MoreHow does physical activity affect the occurrence of major diabetes-related complications?
In a nutshell This study evaluated evidence on the association between physical activity and major diabetes-related complications in patients with diabetes. The authors concluded that physical activity was associated with a reduction in the occurrence of major diabetes-related complications, even if performed at levels lower than recommended. Some...
Read MoreIs an alternative, chemotherapy-free approach possible for patients with acute promyelocytic leukemia?
In a nutshell This study compared the effectiveness of treatment with all-trans retinoic acid (ATRA; Retin-a) and arsenic trioxide (ATO; Trisenox) to ATRA-ATO with chemotherapy (CHT) in patients with newly diagnosed acute promyelocytic leukemia (APL). The data showed that treatment with ATRA-ATO was equally effective as ATRA-ATO plus CHT in these...
Read MoreEvaluating the outcomes of GreenLight laser photoselective vaporization in patients with large prostates for the treatment of benign prostatic hyperplasia.
In a nutshell This study evaluated the outcomes of GreenLight laser photoselective vaporization (PVP) in patients with large prostates for the treatment of benign prostatic hyperplasia (BPH). The data showed that GreenLight PVP was safe and effective in these patients. Some background Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement...
Read MoreEvaluating the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis in patients with a good Endometriosis Fertility Index score.
In a nutshell This study evaluated the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis (EM) in patients with a good Endometriosis Fertility Index (EFI) score. The data showed that both IVF and non-IVF treatments showed similar clinical pregnancy and live birth rates in these...
Read MoreEvaluating the effectiveness and safety of toripalimab in combination with chemotherapy as a first-line treatment for advanced NSCLC.
In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
Read MoreEvaluating the risk factors for ischemic or hemorrhagic stroke recurrence
In a nutshell This study investigated the risk factors for ischemic or hemorrhagic stroke recurrence and the impact of antiplatelet therapy in patients with intracranial hemorrhage (ICH; brain bleed). The data showed that the risk of stroke recurrence is high in these patients. Hypertension (high blood pressure) is a risk factor for ischemic and...
Read MoreEvaluating the effectiveness and safety of radium-223 dichloride treatment in real-world patients with metastatic castration-resistant prostate cancer.
In a nutshell The study evaluated the effectiveness and safety of radium-223 dichloride (Xofigo) treatment in real-world patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that radium-223 dichloride treatment was well tolerated and reduced pain in real-world patients with mCRPC spread to the bone. Some...
Read MoreEvaluating the risk of cardiovascular side effects in cancer patients treated with PD-1/PD-L1 inhibitors.
In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
Read MoreEvaluating the risk of cardiovascular side effects in cancer patients treated with PD-1/PD-L1 inhibitors.
In a nutshell This study evaluated the risk of cardiovascular (CV; heart and blood vessels) side effects in cancer patients treated with PD-1/PD-L1 inhibitors. The data showed that PD-1/PD-L1 inhibitors alone or combined with chemotherapy significantly increased the risk of CV side effects. PD-1/PD-L1 inhibitors combined with chemotherapy significantly...
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