In a nutshell This study evaluated the effectiveness of chemotherapy before surgery for the treatment of patients with resectable colorectal cancer liver metastasis (CRLM). The data showed that the addition of chemotherapy before surgery significantly improved disease-free survival (survival without any signs or symptoms of cancer) but not the...
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In a nutshell This study evaluated the effectiveness and safety of olaparib (Lynparza) with or without cediranib (Recentin) in patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that cediranib combined with olaparib significantly improved survival without cancer worsening compared with olaparib alone in these patients....
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In a nutshell This evaluated the long-term outcomes of nivolumab (Opdivo) plus ipilimumab (Yervoy) versus chemotherapy as first-line treatment for advanced non-small cell lung cancer (NSCLC). The data showed that nivolumab plus ipilimumab increased the long-term overall survival versus chemotherapy in these patients. Some background NSCLC is the most...
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In a nutshell The study evaluated the long-term effectiveness of accelerated partial breast irradiation (ABPI) using multicatheter brachytherapy (BT) with whole-breast irradiation (WBI) in patients with early breast cancer (BC). The study found that ABPI using multicatheter BT was similarly effective with fewer serious side effects compared to...
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In a nutshell This study investigated the occurrence and baseline risk factors of cancer occurrence in patients with rheumatoid arthritis (RA) treated with tofacitinib (Xeljanz) or tumor necrosis factor inhibitors (TNFis). The data showed a higher risk of cancer development with tofacitinib treatment compared to TNFis in these patients. Some...
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In a nutshell This study evaluated the effectiveness of oral azacitidine (Onureg; Oral-AZA) maintenance treatment in older patients with acute myeloid leukemia (AML) in remission. The data showed that Oral-AZA maintenance therapy can be considered in older patients with AML for which hematopoietic stem cell transplantation (HSCT) is not an...
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In a nutshell This study examined the effects of consuming soymilk and probiotics on risk factors related to heart and blood vessel diseases in patients with type 2 diabetes (T2D). The study showed that the consumption of soymilk with probiotics might improve cardiovascular (CV) risk factors in these patients. Some background T2D is a...
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In a nutshell The study evaluated the effectiveness of magnetic stimulation (MS) in urgency urinary incontinence (UUI). The study found that MS showed promising results in treating UUI. Some background Urinary incontinence (UI) is the involuntary leakage of urine. Urinary incontinence is categorized into stress UI, urgency UI, and mixed UI. UUI is a...
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In a nutshell This study evaluated the effectiveness and safety of TAC-302 in patients with detrusor underactivity (DU) and overactive bladder (OAB). The study found that TAC-302 may benefit patients with DU. Some background Overactive bladder (OAB) occurs when the bladder muscle is too active. Instead of staying at rest as urine fills the bladder,...
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In a nutshell This study compared the effectiveness of different intrauterine interventions for women with two or more implantation failures. The data showed that platelet-rich plasma (PRP) was the most effective intrauterine intervention in improving pregnancy outcomes in these women. Some background In vitro fertilization (IVF) is a widely used...
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In a nutshell This study evaluated the effectiveness and safety of taxanes combined with chemotherapy in patients with advanced triple-negative breast cancer (TNBC). This study concluded that the combination of taxanes and chemotherapy is effective with manageable side effects in these patients. Some background TNBC is a subtype of BC that tests...
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In a nutshell The study compared the effectiveness of high- and low-frequency pelvic floor muscle training (PFMT) on urinary incontinence (UI) episode frequency in women with UI. The study found that high-frequency PFMT for 12 weeks was more effective than low-frequency PFMT in these patients. Some background Stress urinary incontinence (SUI) is an...
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