In a nutshell This paper studied whether stroke patients who receive cerebrolysin have improved motor function in their arms after 90 days. Some background A stroke occurs when there is not enough blood supply to the brain. Treatment is usually insufficient and is only successful during the first few hours. After a stroke, there could be...
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Radioemoblization is similarly effective in patients aged over or under 70
In a nutshell This study investigated whether age influenced the effectiveness and safety of radioembolization in patients with colorectal cancer which had spread to the liver. Some background There is a lack of research on treatment options for elderly colorectal cancer (CRC) patients. Elderly patients in the U.S. and Europe are 70-90%...
Read MoreHow does type 1 diabetes affect brain growth in children?
In a nutshell This study used MRI imaging to investigate the effect of T1DM on brain growth and development in young children. Some background Type 1 diabetes (T1D) can cause damage to blood vessels, and has also been associated with cognitive difficulties (problems with reasoning or decision making, for example). T1D that is diagnosed early (by...
Read MoreImproving radiation therapy in advanced non-small cell lung cancer
In a nutshell The current study examined whether targeted radiotherapy benefited survival in patients with stage 3 (spread to the lymph nodes) non-small cell lung cancer. The authors found that 3-dimensional (3D) conformal radiotherapy was associated with increased survival rates in these patients. Some background Many lung cancers are not...
Read MoreFactors associated with disease progression
In a nutshell This study explored factors that could predict disease progression following chemotherapy in breast cancer patients. The authors found that while survival rates were excellent following treatment, patients with faster-growing tumors and those with the luminal B/HER negative or triple negative subtypes had a higher risk of disease...
Read MoreSafety profile: Everolimus
In a nutshell This study examined the long-term safety of everolimus (Afinitor). Everolimus treatment was found to be safe, with adverse (negative) events that were managed by reducing treatment dosage, or breaking treatment for several weeks. Some background Everolimus is a therapy that slows cancer cell growth and increases cell death. In a...
Read MoreThe impact of high estrogen levels on brain function in older type 2 diabetic women
In a nutshell This study examined whether hormone therapy increases the risk of cognitive impairment in elderly type 2 diabetic women. Some background Type 2 diabetes (T2D) increases the risk of cognitive impairment (difficulty remembering, concentrating and making decisions). Patients with T2D also have a higher risk of developing dementia...
Read MoreTwo injections or more? Comparing the effectiveness of insulin degludec and aspart combinations
In a nutshell This study compared the safety and effectiveness of separate insulin degludec and insulin aspart injections versus the two insulins combined in one injection. Some background There are many types of insulin available for patients with type 2 diabetes (T2D). Insulin ranges from rapid-acting to ultra-long acting. Rapid-acting...
Read MoreNew AdVanceXP male sling reviewed
In a nutshell This study reviewed the long-term effectiveness of the AdVanceXP male sling for treatment of urinary incontinence following prostate surgery. The study concluded that the AdVanceXP male sling was effective and safe in the treatment of male stress urinary incontinence. Some background Urinary incontinence is common among men...
Read MoreSurgery and chemotherapy for colorectal cancer spread to the peritoneum
In a nutshell This review analyzed the effectiveness of combined surgery and chemotherapy for colorectal cancer which has spread to the wall of the abdomen. Some background Many colorectal cancer patients are diagnosed after the cancer has already spread. Cancer that has spread to the peritoneum (the abdominal wall) is termed “colorectal...
Read MorePain relief for bone metastasis in prostate cancer
In a nutshell This study compared the effectiveness of ibandronate (Boniva) with the more conventional radiotherapy in reducing metastatic bone pain in prostate cancer. Some background Bone metastasis (cancer spread to the bone) is a common and painful occurrence in prostate cancer. There are a range of treatments available, with radiotherapy...
Read MoreReducing the side effects of docetaxel in prostate cancer
In a nutshell This study examined the efficacy of including an anti-inflammatory hormone, prednisolone (Orapred), with the chemotherapy drug docetaxel (Taxotere) in the treatment of metastatic castration-resistant prostate cancer. The study concluded that prednisolone led to a decrease in specific adverse side effects of this type of...
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