In a nutshell This study examined the effect of alogliptin on the progression of atherosclerosis. Some background Atherosclerosis involves the formation of fats (such as cholesterol) on the walls of arteries and can result in narrowing of the arteries. This leads to increased stiffness of the arteries and increases the risk of...
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The benefits of a canola oil-enriched diet on blood glucose levels
In a nutshell This study examined the effect of canola oil and a low-glycemic-load diet in type 2 diabetic patients. Some background A low-glycemic-load (LGL) diet is recommended for patients with type 2 diabetes (T2D). An LGL diet reduces the risk of cardiovascular disease (CVD – the narrowing or blockage of blood vessels...
Read MoreDoes testosterone replacement therapy have a beneficial effect in type 2 diabetic men with hypogonadotrophic hypogonadism?
In a nutshell This study examined the effect of testosterone replacement therapy on T2D in men with hypogonadotrophic hypogonadism. Some background One third of men with type 2 diabetes (T2D) have hypogonadotrophic hypogonadism (HH). HH is a condition in which the brain fails to produce follicle stimulating hormone (FSH) and leutinizing...
Read MoreMinimally invasive procedures no longer just for small prostates
In a nutshell This study evaluated the effects and safety of transurethral enucleation of the prostate (TUEP) for the treatment of large benign prostatic hyperplasia (BPH). Researchers concluded that TUEP is as safe and effective as the current standard-of-care surgery. Some background Although surgical treatments for BPH have become less...
Read MoreCan nerve stimulation improve urinary function in multiple sclerosis?
In a nutshell This study examined the effectiveness of nerve stimulation in the treatment of urinary incontinence in patients with multiple sclerosis. Researchers concluded that pelvic nerve stimulation (following the LION procedure) can improve symptoms of urinary incontinence in some cases of multiple sclerosis. Some background The LION...
Read MoreSacral nerve stimulation: is intermittent stimulation just as effective?
In a nutshell This study examined a new variation of sacral nerve stimulation used to treat persistent urge urinary incontinence. Researchers concluded that intermittent sacral nerve stimulation was as effective as continuous stimulation in treating urge urinary incontinence. Some background Sacral nerve stimulation (SNM) is a type of...
Read MoreLong term outcomes of a bare-metal stent implantation
In a nutshell This paper studied the very long term outcomes of bare-metal stent implantation. Some background Bare-metal stents are mesh wire tubes placed in blood vessels to allow blood to flow smoothly. After implantation, complications may occur and require target-lesion revascularization. This means that the blood vessel is obstructed...
Read MoreEffect of ivabradine on stable angina
In a nutshell This paper studied the effects of ivabradine (Coralan) in patients with stable angina. Some background Stable angina refers to chest pain on exertion. This can occur because the heart does not receive enough oxygen from blood flow. Atherosclerosis (build-up of substances in the blood vessels) can cause stable angina. Ivabradine...
Read MoreKnow your exercise: abdominal curls, incorrect pelvic-floor muscle training and urinary incontinence
In a nutshell This study examined pelvic-floor muscle activity and bladder position during abdominal exercises. Researchers concluded that a large proportion of women were unable to correctly perform pelvic-floor muscle training. In addition, abdominal curls were found to increase strain on the pelvic-floor, and may contribute to urinary...
Read MoreCan shockwave treatment improve erectile function?
In a nutshell This study evaluated the use of low-intensity shockwave treatment (LIST) for erectile dysfunction. Researchers concluded that LIST is effective at improving erectile function, even in severe cases. Some background The development of phosphodiesterase-5 inhibitors (PDE5i), such as Viagra, have revolutionized the treatment of...
Read MoreA two-way street: Depression and anxiety linked with urinary incontinence
In a nutshell This study investigated the relationship between depression, anxiety and urinary incontinence. Researchers concluded that urinary incontinence is a risk factor for developing depression and anxiety. Similarly, depression or anxiety also increase the risk of developing urinary incontinence. Some background Urinary incontinence (UI)...
Read MoreImmune-related adverse events in nivolumab treated melanoma patients
In a nutshell The authors evaluated immune system-related adverse events and outcomes in melanoma patients treated with nivolumab (Opdivo). Some background In the advanced stage of melanoma (stage 3/4), cancer spreads from the skin to other parts of the body. Immunotherapy is a promising treatment option in advanced melanoma....
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