In a nutshell This study compared the long-term safety and effectiveness of two surgical techniques used to treat prostate enlargement. The researchers concluded that the GreenLight procedure provides a safe and lasting treatment option for benign prostatic hyperplasia (BPH). The procedure was associated with similar long-term effectiveness and...
Read MoreIn a nutshell This study examined the long-term effectiveness of repeated (second) vaginal sling surgery in women with continued urinary incontinence. Researchers concluded that a repeat sling procedure is an effective treatment option for women after an unsuccessful first surgery. Some background Vaginal sling procedures are currently the most...
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In a nutshell This study aimed to determine whether the QRS duration from an ECG could be used to predict long term outcomes in patients with heart disease. The authors concluded that a QRS duration of 120ms or more was capable of predicting the risk of a heart attack and also the risk of death from heart-related causes. Some...
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In a nutshell This study aimed to determine whether exercise capacity affects the outcomes of patients with heart disease. The authors concluded that exercise capacity was not associated with the risk of a heart attack or risk of mortality. Some background Percutaneous coronary intervention (PCI) is a non-surgical procedure used...
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In a nutshell This long-term study evaluated the side-effects of drugs such as doxazosin and finasteride, commonly used to treat urinary symptoms in men with benign prostatic hyperplasia (BPH). Researchers concluded that adverse effects associated with these drugs mainly occur within the first year of treatment. Some background Drugs...
Read MoreIn a nutshell This review examined whether certain beverages contribute to type 2 diabetes. This study conlcuded that sugar sweetened beverages increased the risk of developing type 2 diabetes. Some background Sugar sweetened (SS) beverages likely contribute to obesity and type 2 diabetes (T2D). Artificially sweetened (AS) beverages and...
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In a nutshell This study examined whether depressive symptoms and stress have a negative impact on cardiovascular outcomes in patients with type 2 diabetes. The authors concluded that both depressive symptoms and stress increase the risk of worse cardiovascular outcomes in type 2 diabetes. Some background Cardiovascular disease (CVD) is the...
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In a nutshell This study aimed to determine the safety and efficacy of a combination of the anticancer drugs afatinib (Gilotrif) and nimotuzumab (Theraloc) to treat kinase inhibitor resistant EGFR-mutant-NSCLC. The study found that a combination of these drugs had encouraging potential and an acceptable safety profile. Some background A mutation...
Read MoreIn a nutshell This study looked at the potential benefit of introducing luteinizing hormone (LH) earlier during ovarian stimulation in older women. Starting LH on the earlier date was shown to increase clinical pregnancy rates. Some background There is an increased number of older women (over 35) seeking help to get pregnant. Success rates usually...
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In a nutshell This review compared sulphonylureas and dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes. Some background Patients with type 2 diabetes (T2D) initially produce insulin (hormone which lowers blood sugar levels) but it fails to work in the body. There are many drugs available which can help insulin work in the...
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In a nutshell This study examined the safety and potential effectiveness of using vagus nerve stimulation (VNS) in combination with rehabilitation to improve upper limb function following stroke. It concluded that VNS is safe and has the potential to improve upper limb function when combined with rehabilitation movements. Some background...
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In a nutshell The authors evaluated the effect of percutaneous hepatic perfusion (PHP, a method of treating melanoma that has spread to the liver) with melphalan (Alkeran). This study found that PHP with melphalan improved outcomes in melanoma patients with cancer spread to the liver. Some background In advanced melanoma (stage 3/4), cancer...
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