In a nutshell This study assessed joint symptoms and quality of life two years after total knee replacement surgery in patients with rheumatoid arthritis. The study concluded that rheumatoid arthritis patients undergoing knee replacement surgery experience good outcomes. Some background Total knee replacement surgery is a common treatment for...
Read More
In a nutshell This study investigated the relationship between erectile dysfunction and mortality risk from any other cause. Researchers concluded that erectile dysfunction has important implications on overall health. Some background Erectile dysfunction is linked to a reduced flow of blood to the penis, which can be caused by the narrowing or...
Read More
In a nutshell The authors evaluated the safety and effectiveness of nab-paclitaxel (Abraxene), a chemotherapy, in patients with advanced melanoma. The authors found that nab-paclitaxel was safe, effective, and provided favorable outcomes. Some background In advanced melanoma, cancer spreads from the skin to other parts of the body. This is called...
Read More
In a nutshell This early-phase trial examined whether aleglitazar could be of benefit for the treatment of type 2 diabetes. The authors concluded that aleglitazar improves both blood glucose and cholesterol levels among diabetic patients. As of 2013, all further drug development of aleglitazar was halted...
Read More
In a nutshell This study examined the effectiveness of pelvic-floor muscle training in treating urinary incontinence. The authors of this study concluded that pelvic-floor muscle training is an effective first-line treatment option for urinary symptoms of any type. Some background Pelvic-floor muscle training is often the first, and most...
Read More
In a nutshell This study explored the impact of endometrial thickness on pregnancy rates in patients undergoing in vitro fertilization (IVF). The study concluded that thin endometrial thickness adversely affects ongoing pregnancy rates. Some background Successful pregnancy rates vary widely among couples undergoing in-vitro fertilization (IVF)....
Read More
In a nutshell This paper compared the effect of renal denervation to medication alone in patients with resistant high blood pressure. The authors concluded that renal denervation and intensified medical treatment is similar have similar effects on blood pressure. Some background Resistant hypertension is high blood pressure which cannot be...
Read MoreIn a nutshell This study evaluated the effectiveness of ultrasound exams for the early detection of melanoma spread to the liver. The authors found that regular scans could be used to effectively detect cancer spread to the liver among uveal melanoma patients. Some background Uveal melanoma is a rare cancer of the eye. Uveal melanoma is...
Read More
In a nutshell This paper studied the use of the drugs evolocumab and alirocumab in reducing cholesterol levels in the body. The authors concluded that PCSK9 monoclonal antibodies will be important in treating hypercholesterolemia. Some background Low-density lipoprotein (LDL) is a type of fat present in the blood. LDL binds to and...
Read More
In a nutshell This study examined the potential benefit of early hormone therapy added to intensive radiotherapy in the treatment of men with intermediate-risk local prostate cancer. Overall survival was found to be improved with higher radiation dosage. However, the researchers noted that early hormone therapy does generally not benefit treatment...
Read More
In a nutshell The study investigated the safety and effectiveness of LY2963016 insulin glargine (LY IGlar). It was concluded that LY IGlar is as effective and well-tolerated as current standard insulin glargine (Lantus). Some background Insulin glargine is a long-acting form of insulin. Long-acting insulin is often used to provide stable blood...
Read More
In a nutshell This study examined the safety and effectiveness of ACT balloons in treating stress urinary incontinence in older patients. The researchers concluded that the ACT balloon procedure may benefit older patients experiencing urinary symptoms due to urethral dysfunction. Some background Stress urinary incontinence is often caused by...
Read More
