In a nutshell This paper reviewed the effect of exercise on cardiovascular disease. Many studies found that exercise was beneficial for patients. Some background A sedentary lifestyle (lacking physical activity) is a risk factor for cardiovascular disease (CVD – the narrowing or blockage of arteries which can lead stroke or a heart...
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Can certain drugs lower the heart rate in patients with sleep apnea?
In a nutshell This paper studied the effect of beta-blocker therapy in patients with high blood pressure and untreated sleep apnea. The authors found that beta blockers reduce the increased heart rate caused by sleep apnea. Some background Beta-blockers are a group of drugs that are used in the treatment of heart disease. They reduce...
Read MoreBotox for overactive bladders: Predictors of treatment success
In a nutshell This study investigated whether certain patient characteristics affect treatment success with OnabotA (onabotulinumtoxin-A, botulinum toxin A, or Botox) for overactive bladders. The researchers concluded that gender and symptom severity were reliable predictors of treatment success. Some background Bladder muscle over-activity is...
Read MoreA combination of afatinib and paclitaxel in EGFR-mutant non-small cell lung cancer
In a nutshell This study aimed to determine the efficacy of a combination of the anticancer drugs afatinib (Gilotrif) and paclitaxel (Taxol) to treat non-small cell lung cancer (NSCLC), compared to chemotherapy alone. The study found that a combination of these drugs significantly improved progression free survival (PFS, time from treatment until...
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
Read MoreSearching for patients with chronic wounds to investigate stem-cell therapy
In a nutshell This trial aims to evaluate the effectiveness of fat-derived stem-cells on chronic wounds. The main outcome being investigated is the change in wound size with treatment. The details With diabetes, uncontrolled blood sugar levels can cause nerve and blood vessel damage, which often lead to infections or repeated injuries....
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
Read MoreDealing with cancer pain: Low-dose morphine examined
In a nutshell This study compared weak opioids and low-dose morphine in providing pain relief for moderate cancer pain. Researchers concluded that low-dose morphine is more suitable as pain management for moderate cancer pain than weaker pain relievers. Some background The guidelines for cancer pain relief developed by the World Health...
Read MoreAre knee replacements successful in rheumatoid arthritis patients?
In a nutshell This study assessed joint symptoms and quality of life two years after total knee replacement surgery in patients with rheumatoid arthritis. The study concluded that rheumatoid arthritis patients undergoing knee replacement surgery experience good outcomes. Some background Total knee replacement surgery is a common treatment for...
Read MoreEvaluating the safety and effect of golimumab (Simponi) injections
In a nutshell This study assessed whether golimumab was effective for treating active rheumatoid arthritis despite methotrexate therapy. The study concluded that 78% of patients achieve good response to long-term golimumab treatment. Some background Methotrexate is often the first drug used to treat rheumatoid arthritis. However, in many cases...
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