In a nutshell The authors compared the effect of narrow and wide surgical margins on long-term survival of advanced melanoma patients. The authors found that for melanoma of 2 mm thickness or greater, the surgical margin should be 2 cm. Some background The standard treatment for skin cancer remains surgical removal of the tumor along with some of...
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New immunotherapy for non-small cell lung cancer
In a nutshell This trial assessed the effectiveness of combining a TG4010, a type of immunotherapy, with chemotherapy for non-small-cell lung cancer. It also examined whether TG4010 was more effective in patients with a low level of certain immune cells, called triple positive activated lymphocytes (TrPAL). The study concluded that TG4010 was...
Read MoreCan hormone levels predict bone loss?
In a nutshell This study investigated whether baseline levels of the female hormone FSH (follicle stimulating hormone) can predict bone loss. The study concluded that among premenopausal women with breast cancer treated with chemotherapy, baseline FSH levels were strongly associated with subsequent bone loss. Some background In some...
Read MoreNew longer-acting insulin glargine
In a nutshell This study investigated the safety and effectiveness of a new insulin glargine (Gla-300, Toujeo). The study concluded that Gla–300 provides a similar level of blood sugar control as the current standard insulin glargine (Lantus). Some background Insulin glargine is a long-acting form of insulin. Long-acting insulin is often...
Read MoreDoes celiac disease increase the risk of diabetic complications?
In a nutshell The study investigated whether celiac disease with type 1 diabetes increases the risk of diabetic complications such as retinopathy and kidney disease. It was concluded that celiac disease is a risk factor for retinopathy and kidney disease in patients with type 1 diabetes. Some background Type 1 diabetes is an autoimmune disease...
Read MoreGlucagon: Treating hypoglycemia without the carbs?
In a nutshell This study investigated the effects of glucagon injection on insulin-induced hypoglycemia. The study concluded that glucagon restored blood sugars levels after mild hypoglycemia. Some background Hypoglycemia (very low blood sugar levels) is one of the major barriers of good blood sugar control. It is associated with a range of...
Read MoreCardiovascular diseases associated with disease activity in rheumatoid arthritis
In a nutshell This study explored the influence of other diseases on disease activity in rheumatoid arthritis (RA) patients. The study concluded that cardiovascular (heart and blood vessel) diseases were strongly related to disease activity. Some background RA can cause pain, stiffness, and swelling in the joints. RA disease activity is measured...
Read MoreRepeat sling procedures for recurrent stress urinary incontinence: Effectiveness and risk factors
In a nutshell This study examined the effectiveness of repeat vaginal sling procedures as well as possible risk factors associated with negative surgical outcomes. Researchers concluded that a repeat vaginal sling surgery is an effective treatment option for women who continue to experience incontinence after the first sling procedure. Some...
Read MoreProstate artery embolization also suitable for older men
In a nutshell This study examined prostate artery embolization as a minimally invasive procedure to reduce prostate size in older men with benign prostatic hyperplasia (BPH). The researchers concluded that prostate artery embolization is a safe and effective treatment option for younger as well as older men wit BPH. Some background BPH can lead...
Read MoreLDH as an early predictor of cancer survival
In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
Read MoreLDH as an early predictor of cancer survival
In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
Read MoreLDH as an early predictor of cancer survival
In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
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