In a nutshell This study investigated the effects of adding chemotherapy to trastuzumab (Herceptin) treatment on cognitive (thinking and reasoning) functioning in older patients with HER2-positive (HER2+) breast cancer (BC). The data showed that the addition of chemotherapy did not impact cognitive functioning in these women. Some...
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Treating classic Hodgkin lymphoma in children – a guideline
In a nutshell These guidelines reviewed current recommendations on treating newly diagnosed classic Hodgkin lymphoma (cHL) in children and young adults, and cHL which has returned after previous treatment. Some background Hodgkin lymphoma is cancer of the lymph nodes, which are part of the immune system. It involves cancerous versions of B cells,...
Read MoreCan a vegan diet improve diabetes?
In a nutshell This review looked at whether a vegan diet can improve type 2 diabetes (T2D). It found that a vegan diet can lower glucose (sugar) levels for people with T2D. Some background Vegan diets have become more popular, for both health and ethical reasons. A vegan diet includes plant-based foods and avoids meat, eggs, or dairy. But can a vegan...
Read MoreDoes ICSI benefit couples where men have normal sperm quality?
In a nutshell This trial compared intracytoplasmic sperm injection (ICSI) to conventional in vitro fertilization (IVF) for couples where men have normal sperm quality. It found there was no clear benefit to ICSI over IVF for these couples. Some background IVF is an infertility treatment in which the woman’s ovaries are stimulated to produce...
Read MoreIs olokizumab a useful add-on treatment for rheumatoid arthritis?
In a nutshell This study looked at the safety and effectiveness of olokizumab (Artlegia) as an add-on to methotrexate (Otrexup) treatment in rheumatoid arthritis. It found the olokizumab was associated with significant improvements in RA symptoms and physical function. Some background Rheumatoid arthritis (RA) is a condition affecting...
Read MoreCan deep brain stimulation improve stomach problems in patients with Parkinson’s disease?
In a nutshell This study looked at the effectiveness of deep brain stimulation (DBS) in patients with Parkinson's disease (PD) and stomach problems. It found that DBS was associated with an improvement in stomach disorders and a reduced need for medication. Some background PD is a neurologic condition that can be difficult to treat as...
Read MoreDo eye injections reduce the risk of blindness in patients with severe diabetic eye disease?
In a nutshell This study looked at the use of aflibercept (Eylea) eye injections for the treatment of severe nonproliferative diabetic retinopathy (DR; diabetic eye disease). It found that more than half of the patients treated with aflibercept showed a significant improvement in DR after 6 months. Some background DR is one of...
Read MoreAre patients happy with current overactive bladder treatments?
In a nutshell This study looked at the treatments for overactive bladder (OAB) and how satisfied patients were with current options. It found patients had reduced quality of life due to OAB symptoms and that most patients found non-invasive stimulation treatment comfortable and effective. Some background Overactive bladder (OAB)...
Read MoreEvaluating antibody responses in patients with chronic lymphocytic leukemia after Covid-19 vaccination
In a nutshell The study aimed to investigate antibody responses in patients with chronic lymphocytic leukemia (CLL) after first and second Covid-19 vaccinations. This study concluded that antibody responses of these patients are lower than that of healthy people. Some background B-cell chronic lymphocytic leukemia (CLL) is...
Read MoreIs weight loss due to dulaglutide treatment dose-dependent in patients with type 2 diabetes?
In a nutshell This study compared the effect of administering 1.5 mg, 3 mg, and 4.5 mg of dulaglutide (Trulicity) on overall bodyweight reduction in patients with type 2 diabetes (T2D). The authors concluded that higher doses of dulaglutide caused more weight loss in these patients. Some background Abnormal or excessive levels of fat in the...
Read MoreCan Fluxonorm® food supplement improve the effectiveness of standard therapy for the treatment of lower urinary tract symptoms?
In a nutshell This study assessed the effectiveness of Fluxonorm® herbal supplement when combined with standard therapy for lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The authors concluded that the effectiveness of standard therapy was improved by the addition of Fluxonorm® in patients with...
Read MoreComparing the outcomes of transvesical or posterior robot-assisted radical prostatectomy for localized prostate cancer.
In a nutshell This study compared 2 approaches of robot-assisted radical prostatectomy (RARP) for the treatment of localized prostate cancer (PCa). The authors concluded that both transvesical (T) and posterior (P) approaches had similar results in these patients. Some background Localized prostate cancer (PCa) is cancer that is...
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