In a nutshell This study looked at the use of osimertinib (Tagrisso) for the treatment of EGFR-mutant advanced non-small-cell lung cancer (NSCLC) in a real-world practice. It found that osimertinib was confirmed to improve survival without cancer progressing, while the occurrence of blood clots was more common in a real-world...
Read More
In a nutshell This study looked at the use of peficitinib (Smyraf) for the treatment of rheumatoid arthritis (RA) from the perspective of patients and their doctors. It found that peficitinib improved symptoms of RA and led to increased ability to work and carry out daily activities compared to placebo. Some background RA is a chronic...
Read More
In a nutshell This study compared the use of bulking agents versus surgery for the treatment of stress urinary incontinence (SUI). It found that bulking agents were less effective for SUI compared to surgical treatment. Some background Stress urinary incontinence (SUI) is a condition that is common in women. It leads to leaking of urine...
Read More
In a nutshell This study examined the association of physical activity (PA) and sedentary time (ST) with pain, fatigue, and depressive symptoms over time among survivors of breast cancer (BC). The data showed that lower ST and higher PA is associated with lower depressive symptoms in long-term survivors of BC. Some background BC is one of the most...
Read More
In a nutshell This study evaluated the occurrence and clinical predictors of peripheral neuropathy (PN; nerve damage) in long-term survivors of breast cancer (BC). The data showed that PN is an important long-term consequence of taxane-based chemotherapy in survivors of BC. Some background BC is one of the most common forms of cancer in women....
Read More
In a nutshell This study evaluated the effectiveness and safety of combining cranial radiotherapy (CRT; radiotherapy tot the head) with and without anlotinib (AL3818) for the treatment of patients with non-small cell lung cancer (NSCLC) and brain metastases (BM). The data showed that anlotinib plus CRT significantly improved survival without brain...
Read More
In a nutshell This study determined the percentage of men with benign prostatic hyperplasia (BPH) that still needed BPH medication after surgical therapy for lower urinary tract symptoms (LUTS). The authors concluded that laser enucleation of the prostate (LEP) had the lowest percentage of patients that still needed BPH medication. Some...
Read More
In a nutshell This study examined the association between long-term use of three different tyrosine kinase inhibitors (TKIs) and the occurrence of vascular (blood vessel) adverse events (side effects; VAEs) in patients with chronic myeloid leukemia (CML). The data showed a possibly higher risk of developing VAEs when patients with CML were...
Read More
In a nutshell This study explored the risk factors for fragility fractures in patients with rheumatoid arthritis (RA). The authors concluded that aging, disease-related factors, and previous fracture history are important risk factors for fragility fractures in these patients. Some background RA is a chronic, systemic inflammatory disease that affects...
Read More
In a nutshell This study looked at the use of the Pelviva electro-stimulation device for the treatment of urinary incontinence (UI) in women. It found that the Pelviva device improves UI compared to standard treatment. Some background Urinary incontinence (UI) is a very common problem for women, especially in older age. It involves...
Read More
In a nutshell This study reviewed the initial management of benign prostatic hyperplasia (BPH). Some background BPH is a condition in which the prostate grows and can compress the urethra (the tube that passes urine out of the bladder), leading to difficulty passing urine. Symptoms include needing to urinate frequently,...
Read More
In a nutshell This study compared progesterone injected under the skin to vaginal progesterone after an embryo transfer. It found that under-the-skin progesterone was just as effective as vaginal progesterone, and led to similar pregnancy rates. Some background In vitro fertilization (IVF) is a common infertility treatment that involves transferring...
Read More
