In a nutshell This study is aimed to evaluate the risk of infection for patients who are treated with immune checkpoint inhibitors (ICI) for solid tumors. The study concluded that in frail patients, ICI therapy alone is safer compared to chemotherapy (CT). Some background Immunotherapy is a type of cancer treatment that makes use of the immune...
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In a nutshell This study is aimed to evaluate the risk of infection for patients who are treated with immune checkpoint inhibitors (ICI) for solid tumors. The study concluded that in frail patients, ICI therapy alone is safer compared to chemotherapy (CT). Some background Immunotherapy is a type of cancer treatment that makes use of the immune...
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In a nutshell In this work, the authors evaluated the effectiveness of safinamide (Xadago) on mood in patients with Parkinson's disease (PD). The study showed that safinamide improved PD patients' mood and emotional wellbeing at 6 months. Some background Parkinson's disease (PD) is the second most common...
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In a nutshell This study evaluated treatment options and outcomes for older patients with classic Hodgkin lymphoma (HL). This study concluded that conventional chemotherapy regimens remain a standard of care for these patients. Some background Chemotherapy remains the standard first-line treatment for cHL. One of the most commonly used regimens...
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In a nutshell This study evaluated the safety and effectiveness of teclistamab (JNJ-64007957) for patients with recurrent or unresponsive multiple myeloma (MM). This study concluded that this treatment was safe and showed promising effectiveness for these patients. Some background Multiple myeloma is a type of cancer of the bone marrow that can...
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In a nutshell This study compared the therapeutic benefit of topically applied ON101 (Fespixon) cream to an absorbent dressing (Hydrofiber; ConvaTec Ltd) on wound healing in patients with chronic diabetic foot ulcers (DFUs). The authors concluded that the therapeutic effectiveness of ON101 treatment of DFUs was better compared to absorbent...
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In a nutshell This study looked at the use of transurethral microwave thermotherapy (TUMT) for the treatment of benign prostatic hyperplasia (BPH) compared to transurethral resection of the prostate (TURP). It found that both treatments are similarly effective in managing BPH symptoms. TUMT has fewer side effects than TURP, but it also...
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In a nutshell This study looked at the risk of blood clots in patients with rheumatoid arthritis (RA) treated with biologics. It found that there was no significant increase in the risk of blood clots with biologics compared to other RA treatments. Some background Biologics are a newer type of treatment for RA. They are usually made from...
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In a nutshell This study evaluated short-course radiation therapy (RT) followed by chemotherapy as a non-surgical treatment of patients with rectal cancer (RC). The data showed that treatment with short-course RT and chemotherapy is safe and effective for these patients. Some background Colorectal cancer (CRC) is one of the most common types of...
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In a nutshell This study reported the long-term effects on the health-related quality of life (HR-QoL) of apalutamide (Erleada) in combination with androgen deprivation therapy (ADT) in patients with non-metastatic castration-resistant prostate cancer (nmCRPC). The data showed that apalutamide plus ADT preserved HR-QoL in these patients. Some background...
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In a nutshell This study evaluated whether patients with non-small-cell lung cancer (NSCLC) having genetic mutations could benefit from epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) therapy after surgery. The data showed that EGFR-TKI therapy after surgery significantly improved survival without disease progression in...
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In a nutshell This study investigated the occurrence of fatigue (tiredness) in patients with early rheumatoid arthritis (RA) and identified predictors of fatigue after 24 months. The data showed that patients with early disease remission had a rapid, sustained reduction in fatigue and that low disease activity at diagnosis predicted a higher risk...
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