In a nutshell The authors investigated the health-related quality of life (HRQoL) 1 year after the diagnosis of diffuse large B-cell lymphoma (DLBCL). The study found that HRQoL is affected differently in women and men survivors of DLBCL 1 year after diagnosis and that aspects of HRQoL need to be addressed and managed in these...
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In a nutshell This study evaluated the effectiveness and safety of sequential administration of high dose aldesleukin (Interleukin-2; Proleukin) and ipilimumab (Yervoy) in patients with metastatic melanoma. The data showed that high dose aldesleukin and ipilimumab were effective and safe when administered sequentially in these patients. Some background...
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In a nutshell This study evaluated the effectiveness and safety of adding daratumumab (Darzalex) to lenalidomide (Revlimid) and dexamethasone (Decadron) therapy for patients with newly diagnosed multiple myeloma (MM). The data showed that adding daratumumab to the lenalidomide and dexamethasone (Rd) regimen was safe and improved...
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In a nutshell This study compared the effectiveness of epirubicin (Ellence) and cyclophosphamide (Cytoxan) plus paclitaxel (Taxol)/docetaxel (Taxotere) (taxanes) (ECT) versus carboplatin (Paraplatin) plus taxanes (TP) regimens in patients with early-stage triple-negative breast cancer (TNBC). The data showed that both treatment regimens showed...
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In a nutshell This study compared the health-related quality of life (HR-QoL) outcomes between pembrolizumab (Keytruda) and brentuximab vedotin (BV; Adcetris) in patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The data showed that the pembrolizumab improved the HR-QoL outcomes compared to BV in these patients. Some...
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In a nutshell This study investigated if a salt substitute could reduce the risk of stroke and cardiovascular (CV) events in patients with hypertension (high blood pressure). The data showed that the salt substitute reduced the risks of stroke, major CV events, and death from any cause compared to regular salt in patients with hypertension. Some...
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In a nutshell This study evaluated the effectiveness and safety of the ND0612 delivery system of levodopa/carbidopa (Sinemet) in patients with Parkinson's disease (PD). The authors showed that the system was well-tolerated and safe and that it reduced the fluctuations of the levodopa plasma levels. Some background Parkinson's...
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In a nutshell This study explored the role of maintenance therapy after a second autologous hematopoietic cell transplant (AHCT2) in patients with multiple myeloma (MM). The data showed that maintenance therapy after AHCT2 was associated with better outcomes in these patients. Some background MM is commonly hard-to-treat. Many patients are treated...
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In a nutshell This study highlights psychosocial recommendations for survivors of prostate cancer (PCa) and their partners during sexual rehabilitation. The authors concluded that biopsychosocial programs are beneficial for providing educational support and psychosocial counseling to patients with erectile dysfunction in addition to existing biomedical...
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In a nutshell This study evaluated the effectiveness and safety outcomes of durvalumab (Imfinzi) maintenance after chemoradiotherapy (CRT) in real-world patients with unresectable stage 3 non-small-cell lung cancer (NSCLC). The data showed that durvalumab maintenance after CRT was safe and showed good short-term survival outcomes in these...
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In a nutshell This study evaluated the effectiveness and safety of ixazomib (Ninlaro) as maintenance therapy after bortezomib (Velcade)-based induction therapy in real-world patients with multiple myeloma (MM). The data showed that the outcomes of these patients in the real-world setting were good with manageable side effects. Some background...
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In a nutshell This study evaluated the effectiveness of radiotherapy (RT) plus androgen receptor-targeted therapy (ARTT) on oligo-progressive sites for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that RT on oligo-progressive sites was safe and effective in prolonging treatment with ARTT in...
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