In a nutshell This study evaluated the antibody response and side effects associated with COVID-19 vaccines administration in patients with type 1 (T1D) and type 2 diabetes (T2D), people without diabetes. The data showed similar immune responses in patients with and without diabetes after the second COVID-19 vaccine,...
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In a nutshell This study evaluated the long-term impact of 10-kHz spinal cord stimulation (SCS) in patients with painful diabetic neuropathy (PDN; nerve disease) and refractory symptoms. The data supported the use of 10-kHz SCS for important, durable pain relief over 12 months in these patients. Some background Diabetic sensorimotor peripheral...
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In a nutshell This study investigated the effectiveness and safety of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with tadalafil (Cialis) and L-arginine for the treatment of patients with mild and moderate erectile dysfunction (ED). The data showed that daily therapy with tadalafil and L-arginine increased the...
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In a nutshell This study evaluated the safety and effectiveness of blinatumomab (Blincyto) for the treatment of children with relapsed or refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL). The data showed that blinatumomab was safe and effective for these patients. Some background B-ALL is a type of cancer in which the body makes...
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In a nutshell This study evaluated the risk factors associated with acute radiation dermatitis (ARD; skin irritation) after radiotherapy (RT) in patients with breast cancer (BC). The data showed that patients with diabetes, smokers, and those with a body mass index (BMI; a measure of body weight in relation to height) of more than 25 kg/m2 had a...
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In a nutshell This study aimed to investigate the outcomes for acute myeloid leukemia (AML) patients treated with venetoclax (Venclexta) and azacitidine (Vidaza) who achieved complete remission (CR) and minimal measurable residual disease (MRD) after treatment. This study concluded that patients who achieved both CR and minimal...
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In a nutshell This study aimed to investigate the effect of idecabtagene vicleucel (ABECMA; ide-cel) treatment on health-related quality of life (HR-QoL) in patients with relapsed or refractory (r/r) multiple myeloma (MM). This study concluded that this treatment improves HR-QoL for these patients. Some...
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In a nutshell This study evaluated the effectiveness and safety of vagus nerve stimulation (VNS) for improving upper limb function in patients after ischemic stroke. The data showed that VNS was safe and improved upper limb function in these patients. Some background An ischemic stroke happens when blood flow through the blood vessels that supply...
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In a nutshell This study evaluated the effectiveness and safety of ropinirole (Requip) for the treatment of patients with Parkinson’s disease (PD). The data showed that ropinirole was effective in improving motor function and daily living of patients with PD but was associated with an increase in side effects. Some background Parkinson's...
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In a nutshell This study evaluated the effectiveness of immunotherapy in advanced lung cancer (LC) patients with and without brain metastases (BMs). The data showed that immunotherapy significantly improved overall survival in LC patients with and without BMs. Some background In 20-40% of patients with advanced LC, the cancer spreads from the lung to...
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In a nutshell This study evaluated the effectiveness of trilaciclib (Cosela) given before gemcitabine (Gemzar) plus capecitabine (Xeloda) (GC) chemotherapy regimen in patients with metastatic triple-negative breast cancer (mTNBC). The data showed that trilaciclib given before GC chemotherapy regimen was effective and significantly improved overall...
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In a nutshell This study identified clinical risk factors that resulted in the failure of dutasteride (Avodart) add-on treatment to alpha-adrenergic antagonists for patients with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). The authors concluded that an intravesical prostatic protrusion (IPP; the enlargement of the...
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