In a nutshell This study determined the effect of varying carbohydrate and saturated fat dietary contents on cardiovascular disease (CVD) risk factors during weight-loss maintenance. The authors concluded that restriction of carbohydrates provided improved insulin resistance on lipoprotein metabolism, without unwanted side effects on low-density...
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Evaluating the effectiveness and safety of etoposide combined with cytarabine plus G-CSF for stem cell mobilization in patients with multiple myeloma.
In a nutshell This study evaluated the effectiveness and safety of etoposide (Etopophos) combined with cytarabine (Cytosar-U) plus granulocyte colony-stimulating factor (G-CSF, Neupogen) in patients with multiple myeloma (MM) for stem cell mobilization. The data showed that etoposide combined with cytarabine plus G-CSF was safe and effective for the...
Read MoreEvaluating the effectiveness and safety of Rezum water vapor therapy in real-world patients with benign prostatic hyperplasia.
In a nutshell This study evaluated the effectiveness and safety of Rezum water vapor therapy in real-world patients with benign prostatic hyperplasia (BPH). The data showed that Rezum water vapor therapy was safe and effective in these patients. Some background Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate...
Read MoreEvaluating COVID-19 vaccination in immunocompromised patients with blood cancers
In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower immune...
Read MoreEvaluating COVID-19 vaccination in immunocompromised patients with blood cancers
In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower immune...
Read MoreEvaluating COVID-19 vaccination in immunocompromised patients with blood cancers
In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower...
Read MoreEvaluating COVID-19 vaccination in immunocompromised patients with blood cancers
In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower immune...
Read MoreComparing the effectiveness of surgery with and without oral uracil and tegafur plus leucovorin chemotherapy for patients with stage II colon cancer.
In a nutshell This study compared the effectiveness of surgery with and without chemotherapy with uracil and tegafur (Uftoral; UFT) plus leucovorin (LV; folinic acid) in patients with stage II colon cancer. This study concluded that surgery with UFT/LV chemotherapy significantly improved survival outcomes in these patients. Some...
Read MoreEvaluating the effectiveness and safety of 225Ac-PSMA-617 after treatment with androgen deprivation therapy in patients with metastatic castration-resistant prostate cancer.
In a nutshell This study evaluated the effectiveness and safety of actinium-225 [225Ac]-PSMA-617 (225AcPSMA) after treatment with androgen deprivation therapy (ADT) in patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that 225AcPSMA treatment showed a higher response with manageable effects in these patients. Some...
Read MoreEvaluating the effectiveness and safety of first-line tyrosine kinase inhibitor with or without radiotherapy for the treatment of patients with oligometastatic EGFR-mutated NSCLC.
In a nutshell This study evaluated the effectiveness and safety of first-line tyrosine kinase inhibitors (TKIs) with or without radiotherapy (RT) for the treatment of patients with oligometastatic (OM) non-small-cell lung cancer (NSCLC) having genetic mutations in the epidermal growth factor receptor (EGFR). The data showed that TKI plus RT was safe and...
Read MoreEvaluating the effectiveness of antiresorptive drugs on bone mineral density in postmenopausal women with early-stage breast cancer receiving treatment with aromatase inhibitors.
In a nutshell This study evaluated the effectiveness of antiresorptive drugs on bone mineral density (BMD) in postmenopausal women with early-stage breast cancer (BC) receiving treatment with aromatase inhibitors (AIs). The data showed that denosumab (Prolia) and zoledronic acid (Aclasta) were the most effective antiresorptive treatment options to...
Read MoreCan a ketogenic diet affect patients newly diagnosed with type 2 diabetes that are obese or overweight?
In a nutshell This study observed the effectiveness of a ketogenic diet (KD) in patients newly diagnosed with type 2 diabetes (T2D) that were overweight or obese. The authors concluded that a DK can control body weight, blood glucose, and blood lipids (fats) in these patients but long-term adherence is a challenge. Some background...
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