In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower...
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In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower immune...
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In a nutshell This study compared the effectiveness of surgery with and without chemotherapy with uracil and tegafur (Uftoral; UFT) plus leucovorin (LV; folinic acid) in patients with stage II colon cancer. This study concluded that surgery with UFT/LV chemotherapy significantly improved survival outcomes in these patients. Some...
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In a nutshell This study evaluated the effectiveness and safety of actinium-225 [225Ac]-PSMA-617 (225AcPSMA) after treatment with androgen deprivation therapy (ADT) in patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that 225AcPSMA treatment showed a higher response with manageable effects in these patients. Some...
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In a nutshell This study evaluated the effectiveness and safety of first-line tyrosine kinase inhibitors (TKIs) with or without radiotherapy (RT) for the treatment of patients with oligometastatic (OM) non-small-cell lung cancer (NSCLC) having genetic mutations in the epidermal growth factor receptor (EGFR). The data showed that TKI plus RT was safe and...
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In a nutshell This study evaluated the effectiveness of antiresorptive drugs on bone mineral density (BMD) in postmenopausal women with early-stage breast cancer (BC) receiving treatment with aromatase inhibitors (AIs). The data showed that denosumab (Prolia) and zoledronic acid (Aclasta) were the most effective antiresorptive treatment options to...
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In a nutshell This study observed the effectiveness of a ketogenic diet (KD) in patients newly diagnosed with type 2 diabetes (T2D) that were overweight or obese. The authors concluded that a DK can control body weight, blood glucose, and blood lipids (fats) in these patients but long-term adherence is a challenge. Some background...
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In a nutshell This study assessed the safety and effectiveness of oral, high-dose daily vitamin D3 for the prevention of diabetes in adults at high risk for type 2 diabetes (T2D). The authors concluded that oral, high-dose daily vitamin D3 at a dose of 4000 IU was safe and well-tolerated in patients with prediabetes that were overweight or...
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In a nutshell This study compared the effectiveness of common immuno-chemotherapy (ICT) treatments for advanced follicular lymphoma (FL) for front-line therapy. The study showed that obinutuzumab (Gazyva; G) combined with bendamustine (Treanda; Benda) (G-Benda-G regimen) had the best survival without cancer worsening in patients with advanced...
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In a nutshell This study aimed to investigate infusion reactions and the effectiveness of the combination of obinutuzumab (Gazyva) and chlorambucil (Leukeran) in patients with chronic lymphocytic leukemia (CLL). This study concluded that first dose infusion reactions with obinutuzumab can be reduced by using chlorambucil first and by using a very...
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In a nutshell This study assessed the link between metformin (Glucophage) use in hospitalized and non-hospitalized patients with diabetes and different outcomes due to coronavirus disease 2019 (COVID-19). The study showed that metformin use was associated with a protective effect in COVID-19 outcomes in patients with type 2 diabetes (T2D). Some...
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In a nutshell This study analyzed the impact of cognitive-motor dual-task training (CMDT) on patients with chronic stroke. The authors concluded that CMDT had beneficial effects on balance ability, gait, and upper limb function in patients with chronic stroke. Some background A stroke involves an interruption or slowing of blood flow and oxygen to the...
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