In a nutshell This study investigated the effectiveness and safety outcomes of administering radiotherapy (RT) at the same time as DCEP salvage chemotherapy in patients with unresponsive multiple myeloma (MM). This study concluded that RT administered at the same time with DCEP salvage chemotherapy was effective and well-tolerated by most of the...
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Evaluating the bone mineral density screening rates and their association with fracture rates among older men with prostate cancer receiving androgen deprivation therapy.
In a nutshell This study evaluated the bone mineral density (BMD) screening rates and their association with fracture rates among older men with prostate cancer (PC) receiving androgen deprivation therapy (ADT). The data showed that BMD screening is associated with a lower major fracture risk in these patients. Some background Prostate...
Read MoreEvaluating the long-term effects of a moderate low-carbohydrate diet on blood glucose control and liver function in patients with type 2 diabetes
In a nutshell This study evaluated the long-term effects of a moderate low-carbohydrate diet (LCD) on blood glucose control and liver function in patients with type 2 diabetes (T2D). The data showed that patients on a moderate LCD diet showed better blood glucose control and liver function over the long term than patients on a traditional diabetic...
Read MoreEvaluating the effect of vitamin D supplementation on in vitro fertilization outcomes
In a nutshell This study evaluated the effect of vitamin D supplementation on in vitro fertilization (IVF) outcomes. The data showed that vitamin D supplementation significantly improved the biochemical pregnancy rate in these patients. Some background Infertility is a common problem worldwide. In vitro fertilization (IVF) has improved fertility...
Read MoreEvaluating the effectiveness of different types of acupuncture therapies in the treatment of rheumatoid arthritis.
In a nutshell This analysis compared the effectiveness of different acupuncture therapies combined with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis (RA). The data indicated that RA disease activity was most improved by combining electro-acupuncture and DMARDs while fire-needle or moxibustion plus DMARDs...
Read MoreEvaluating outcomes after salvage therapy using chemotherapy or allogeneic stem cell transplantation for unresponsive acute myeloid leukemia
In a nutshell This study aimed to investigate the impact of salvage treatment using either chemotherapy (CT) or allogeneic hematopoietic stem cell transplant (allo-HSCT) on the overall outcome in patients with refractory (unresponsive) acute myeloid leukemia (AML). This study concluded that allo-HSCT benefits these patients and that direct...
Read MoreEvaluating the effectiveness and safety of eplerenone treatment for patients with diabetic kidney disease.
In a nutshell This study assessed the effectiveness and safety of eplerenone (Inspra) treatment for diabetic nephropathy (DN; diabetic kidney disease) in patients with type 2 diabetes (T2D). The data showed that eplerenone can be an effective supplement to existing clinical treatment in patients with DN. Some background DN is kidney damage...
Read MoreCan teneligliptin be safely and effectively given to patients with inadequately controlled type 2 diabetes by triple oral antidiabetic drug treatment?
In a nutshell This study compared the effectiveness and safety of teneligliptin (Tenelia) to placebo in patients with type 2 diabetes (T2D) that was inadequately controlled with triple oral antidiabetic drugs (OADs). The study showed that teneligliptin may be considered as a fourth add-on OAD treatment in these patients. Some background T2D is...
Read MoreEvaluating the effectiveness of daratumumab-containing regimens in patients with multiple myeloma who are unresponsive to lenalidomide maintenance therapy.
In a nutshell This study evaluated the effectiveness of daratumumab (Darzalex)-containing regimens in patients with multiple myeloma (MM) unresponsive to lenalidomide (Revlimid) maintenance therapy. The data showed that daratumumab-containing therapies are effective regimens in these patients. Some background Multiple myeloma (MM) is a type...
Read MoreEvaluating the effectiveness of adding dutasteride to tadalafil for improving lower urinary tract symptoms in patients with benign prostatic hyperplasia.
In a nutshell This study evaluated the effectiveness of adding dutasteride (Avodart) to tadalafil (Cialis) for the treatment of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The data showed that adding dutasteride to tadalafil is a good treatment option for improving LUTS in these patients. Some background...
Read MoreEvaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.
In a nutshell This study evaluated the impact of immune checkpoint inhibitors (ICIs) on COVID-19 outcomes in patients with cancer. The data showed that the use of ICI treatment before COVID-19 infection does not affect the disease severity or survival outcomes. This study supports the continued use of ICIs in cancer patients during the pandemic. Some...
Read MoreEvaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.
In a nutshell This study evaluated the impact of immune checkpoint inhibitors (ICIs) on COVID-19 outcomes in patients with cancer. The data showed that the use of ICI treatment before COVID-19 infection does not affect the disease severity or survival outcomes. This study supports the continued use of ICIs in cancer patients during the...
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