In a nutshell The study investigated whether radiotherapy (RT) addedd to standard of care (SOC) treatment would be beneficial for men with metastatic (spread) prostate cancer (mPC). The study showed that adding RT to SOC improved the survival of men with low burden (defined as fewer than 10 lesions, no greater than 3cm in diameter) mPC. Some...
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Evaluating the effectiveness of laser photocoagulation plus anti-VEGF treatment in patients with diabetic eye disease.
In a nutshell This study evaluated the effectiveness of panretinal photocoagulation (PRP) plus intravitreal anti-VEGF treatment versus PRP alone for the treatment of patients with diabetic retinopathy (DR; diabetic eye disease). The data showed that PRP with anti-VEGF combination treatment improved vision without an increase in side effects...
Read MoreEvaluating the long-term effectiveness of ibrutinib–rituximab treatment versus standard chemoimmunotherapy in patients with chronic lymphocytic leukemia.
In a nutshell This study investigated the long-term effectiveness of ibrutinib (Imbruvica)–rituximab (Rituxan) (IR) treatment versus standard chemoimmunotherapy (CIT) in patients aged 70 or younger with previously untreated chronic lymphocytic leukemia (CLL). The data showed that the IT regimen significantly improved the survival outcomes compared...
Read MoreEvaluating the effectiveness and safety of adding PolyPepI1018 peptide vaccine to maintenance therapy in patients with microsatellite stable metastatic colorectal cancer.
In a nutshell This study evaluated the effectiveness and safety of adding PolyPepI1018 peptide vaccine to fluoropyrimidine/bevacizumab (Avastin) maintenance therapy in patients with microsatellite stable (MSS) metastatic colorectal cancer (mCRC). The data showed that PolyPEPI1018 added to maintenance therapy was safe and associated with specific...
Read MoreEvaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.
In a nutshell This study investigated the effectiveness and safety of fractionated stereotactic radiation therapy (FSRT) for patients with small and moderate-sized brain metastases (BM). The data showed that FSRT was safe and effective in patients with BM of any size with excellent local control. Some background Stereotactic radiosurgery (SRS) is...
Read MoreEvaluating treatment outcomes of fractionated stereotactic radiotherapy in patients with small and moderate-sized brain metastases.
In a nutshell This study investigated the effectiveness and safety of fractionated stereotactic radiation therapy (FSRT) for patients with small and moderate-sized brain metastases (BM). The data showed that FSRT was safe and effective in patients with BM of any size with excellent local control. Some background Stereotactic radiosurgery (SRS) is...
Read MoreComparing the effectiveness and safety of percutaneous coronary intervention versus coronary artery bypass grafting in patients with left main coronary artery disease.
In a nutshell This study compared the effectiveness and safety of percutaneous coronary intervention (PCI) using drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) in patients with left main (LM) coronary artery disease (CAD). The data showed that both treatments were associated with a similar risk of heart attack, stroke, and death....
Read MoreEvaluating the effectiveness and safety outcomes of administering radiotherapy at the same time with DCEP salvage chemotherapy in patients with multiple myeloma.
In a nutshell This study investigated the effectiveness and safety outcomes of administering radiotherapy (RT) at the same time as DCEP salvage chemotherapy in patients with unresponsive multiple myeloma (MM). This study concluded that RT administered at the same time with DCEP salvage chemotherapy was effective and well-tolerated by most of the...
Read MoreEvaluating the bone mineral density screening rates and their association with fracture rates among older men with prostate cancer receiving androgen deprivation therapy.
In a nutshell This study evaluated the bone mineral density (BMD) screening rates and their association with fracture rates among older men with prostate cancer (PC) receiving androgen deprivation therapy (ADT). The data showed that BMD screening is associated with a lower major fracture risk in these patients. Some background Prostate...
Read MoreEvaluating the long-term effects of a moderate low-carbohydrate diet on blood glucose control and liver function in patients with type 2 diabetes
In a nutshell This study evaluated the long-term effects of a moderate low-carbohydrate diet (LCD) on blood glucose control and liver function in patients with type 2 diabetes (T2D). The data showed that patients on a moderate LCD diet showed better blood glucose control and liver function over the long term than patients on a traditional diabetic...
Read MoreEvaluating the effect of vitamin D supplementation on in vitro fertilization outcomes
In a nutshell This study evaluated the effect of vitamin D supplementation on in vitro fertilization (IVF) outcomes. The data showed that vitamin D supplementation significantly improved the biochemical pregnancy rate in these patients. Some background Infertility is a common problem worldwide. In vitro fertilization (IVF) has improved fertility...
Read MoreEvaluating the effectiveness of different types of acupuncture therapies in the treatment of rheumatoid arthritis.
In a nutshell This analysis compared the effectiveness of different acupuncture therapies combined with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis (RA). The data indicated that RA disease activity was most improved by combining electro-acupuncture and DMARDs while fire-needle or moxibustion plus DMARDs...
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