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Evaluating the effectiveness and safety of adebrelimab plus standard chemotherapy as first-line treatment for extensive-stage small cell lung cancer.

Evaluating the effectiveness and safety of adebrelimab plus standard chemotherapy as first-line treatment for extensive-stage small cell lung cancer.

Posted by on Oct 16, 2022 in Lung cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety outcomes of adebrelimab (SHR-1316) plus carboplatin (Paraplatin) and etoposide (Etopophos)-based chemotherapy as first-line treatment for extensive-stage (ES) small-cell lung cancer (SCLC). The data showed that adebrelimab added to standard chemotherapy as first-line treatment...

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Evaluating the effectiveness of tadalafil alone, silodosin alone, and the combination of both in the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.

Evaluating the effectiveness of tadalafil alone, silodosin alone, and the combination of both in the treatment of lower urinary tract symptoms in patients with benign prostatic hyperplasia.

Posted by on Oct 16, 2022 in Benign prostatic hyperplasia | 0 comments

In a nutshell This study evaluated the effectiveness of tadalafil (Cialis) alone, silodosin (Rapaflo) alone, and the combination of both in the treatment of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The data showed that a combination of tadalafil plus silodosin is more effective than either drug alone in...

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A review of mRNA COVID-19 vaccines in patients with chronic lymphocytic leukemia

A review of mRNA COVID-19 vaccines in patients with chronic lymphocytic leukemia

Posted by on Oct 16, 2022 in Leukemia | 0 comments

In a nutshell This review aimed to assess the strength of previous evidence and to better understand the current role of SARS-CoV-2 vaccination in patients with chronic lymphocytic leukemia (CLL).  This review concluded that there is an overall lower seroconversion rate for SARS-CoV-2 vaccination in these patients as compared with the general...

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Comparing the effectiveness and safety of prostate-only versus pelvic radiotherapy for patients with prostate cancer spread to nearby lymph nodes.

Comparing the effectiveness and safety of prostate-only versus pelvic radiotherapy for patients with prostate cancer spread to nearby lymph nodes.

Posted by on Oct 16, 2022 in Prostate cancer | 0 comments

In a nutshell This study compared the safety and effectiveness of whole-pelvis radiotherapy (WPRT) and prostate-only radiotherapy (PORT) in patients with node-positive prostate cancer (PC) (PC that has spread to nearby lymph nodes). The study found that WPRT improves survival without relapse in these patients, with more short-term...

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Is the addition of low-dose prednisolone more beneficial than harmful to older patients with rheumatoid arthritis?

Is the addition of low-dose prednisolone more beneficial than harmful to older patients with rheumatoid arthritis?

Posted by on Oct 16, 2022 in Rheumatoid Arthritis | 0 comments

In a nutshell This study assessed the effectiveness and safety of daily administered prednisolone (Prelone) at a dose of 5 mg, as an add-on to the standard of care (SOC) in older patients with rheumatoid arthritis (RA). The authors concluded that low-dose prednisolone added to SOC had long-term benefits in these patients with a favorable balance of...

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Can walking speed be improved with foot-ankle therapeutic exercises in patients with diabetic nerve disease?

Can walking speed be improved with foot-ankle therapeutic exercises in patients with diabetic nerve disease?

Posted by on Oct 16, 2022 in Diabetes mellitus | 0 comments

In a nutshell This study investigated the effects of foot-ankle therapeutic exercises on daily physical activity and gait (walking) speed in people with diabetic peripheral neuropathy (DPN). The data showed that at 12 weeks, these exercises led to improvements in fast walking speeds and quality of life compared to usual care. Some background...

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How safe and effective is dapagflozin in patients with type 2 diabetes based on blood pressure levels?

How safe and effective is dapagflozin in patients with type 2 diabetes based on blood pressure levels?

Posted by on Oct 16, 2022 in Diabetes mellitus | 0 comments

In a nutshell This study analyzed the safety and effectiveness of dapagliflozin (Farxiga) in patients with type 2 diabetes (T2D) across different ranges of baseline systolic blood pressure (SBP; blood pressure when the heart beats). The data suggested that dapagliflozin reduced the risk of hospitalization for heart failure (HHF) and kidney-related...

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Comparing the effectiveness and safety of an early versus a delayed invasive strategy in patients with non-ST elevation acute coronary syndrome.

Comparing the effectiveness and safety of an early versus a delayed invasive strategy in patients with non-ST elevation acute coronary syndrome.

Posted by on Oct 13, 2022 in Coronary artery disease | 0 comments

In a nutshell This study compared the effectiveness and safety of an early and a delayed invasive strategy (IS) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). The data showed that there were no significant differences in the risk of death, heart attacks, stroke rates, major bleeding, or revascularization between early and delayed...

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Evaluating the long-term effectiveness and safety of 3-month versus 6-month modified FOLFOX/CAPOX treatment after surgery in patients with stage 3 colon cancer.

Evaluating the long-term effectiveness and safety of 3-month versus 6-month modified FOLFOX/CAPOX treatment after surgery in patients with stage 3 colon cancer.

Posted by on Oct 13, 2022 in Colorectal cancer | 0 comments

In a nutshell This study evaluated the long-term effectiveness and safety of 3-month versus 6-month modified FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) or CAPOX (capecitabine and oxaliplatin) treatment after surgery in patients with stage 3 colon cancer. The data showed that 3-month modified FOLFOX/CAPOX treatment was as effective and safe as...

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Evaluating the effectiveness and safety of low-intensity extracorporeal shock wave therapy for patients with diabetes and erectile dysfunction.

Evaluating the effectiveness and safety of low-intensity extracorporeal shock wave therapy for patients with diabetes and erectile dysfunction.

Posted by on Oct 7, 2022 in Erectile dysfunction | 0 comments

In a nutshell This study evaluated the effectiveness and safety of low-intensity extracorporeal shock wave therapy (Li-ESWT) for patients with diabetes and erectile dysfunction (ED). The data showed that Li-ESWT was safe and effective in improving the symptoms of ED in these patients. Some background Erectile dysfunction (ED) consists of the inability...

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Evaluating the effectiveness and safety of low-intensity extracorporeal shock wave therapy for patients with diabetes and erectile dysfunction.

Evaluating the effectiveness and safety of low-intensity extracorporeal shock wave therapy for patients with diabetes and erectile dysfunction.

Posted by on Oct 7, 2022 in Diabetes mellitus | 0 comments

In a nutshell This study evaluated the effectiveness and safety of low-intensity extracorporeal shock wave therapy (Li-ESWT) for patients with diabetes and erectile dysfunction (ED). The data showed that Li-ESWT was safe and effective in improving the symptoms of ED in these patients. Some background Erectile dysfunction (ED) consists of the inability...

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