In a nutshell This study evaluated the effect of patient-reported physical and mental health status before revascularization procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) on their long-term outcomes in patients with coronary artery disease (CAD). The data showed that...
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Comparing the effects of a ketogenic diet versus a Mediterranean diet on glucose control in patients with prediabetes and type 2 diabetes.
In a nutshell This study compared the effects of a ketogenic diet (KD) versus a Mediterranean diet (MD) on glucose control in patients with prediabetes and type 2 diabetes (T2D). The data showed that the less restrictive MD was as effective in controlling glucose as a KD and likely more likely to be maintained in the long term. There...
Read MoreEvaluating the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected NSCLC.
In a nutshell This study evaluated the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected non-small cell lung cancer (NSCLC). The authors concluded that the combination of cisplatin (Platinol)-vinorelbine (Nevelbine) improved the outcomes of these patients. Also, the...
Read MoreEvaluating the effectiveness of different ovarian stimulation protocols for patients with poor ovarian response.
In a nutshell This study evaluated the effectiveness of different ovarian stimulation protocols for patients with poor ovarian response (POR). The data showed that delayed start gonadotropin-releasing hormone (GnRH) antagonist and microdose GnRH agonist were the two most effective regimens for the treatment of these patients. Some background Many...
Read MoreComparing the effectiveness and safety of combined therapy of atezolizumab with nab-paclitaxel in patients with triple negative breast cancer
In a nutshell The study compared the effectiveness and safety of atezolizumab (Tecentriq) and nab-paclitaxel (Abraxane) combined therapy with nab-paclitaxel alone in patients with triple-negative breast cancer (TNBC). The study found that combined therapy was more effective than single therapy but it had more serious side effects in these...
Read MoreEvaluating the effectiveness of massage therapy for chemotherapy-induced nerve disease
In a nutshell The study evaluated the effectiveness of massage therapy for chemotherapy-induced peripheral neuropathy (CIPN) in patients with breast and gastrointestinal (GI) cancer. The main finding of the study was that intensive massage therapy 3 times a week showed promising results in these patients. Some background There are many...
Read MoreEvaluating the effectiveness of massage therapy for chemotherapy-induced nerve disease
In a nutshell The study evaluated the effectiveness of massage therapy for chemotherapy-induced peripheral neuropathy (CPIN) in patients with breast and gastrointestinal (GI) cancer. The main finding of the study was that intensive massage therapy 3 times a week showed promising results in these patients. Some background There are many cancer...
Read MoreEvaluating treosulfan vs reduced-intensity busulfan conditioning for allogeneic hematopoietic cell transplantation in older patients with acute myeloid leukemia
In a nutshell This study aimed to compare the outcomes of allogeneic hematopoietic cell transplant (alloHCT) for older patients with acute myeloid leukemia (AML) using treosulfan (Trecondi) compared to reduced intensity busulfan (Myleran) conditioning. This study concluded that treosulfan conditioning appears to be more suitable for...
Read MoreHow effective and safe is rituximab biosimilar HLX01 in patients with moderate to severe rheumatoid arthritis?
In a nutshell This study evaluated the effectiveness and safety of rituximab (Rituxan) biosimilar HLX01 combined with methotrexate (MTX; Trexall) in patients with moderate to severe rheumatoid arthritis (RA) following inadequate responses to MTX. The study showed that HLX01 added to MTX resulted in improvements compared to placebo in these...
Read MoreHow beneficial is the addition of metformin to insulin therapy for adolescents with type 1 diabetes?
In a nutshell This study assessed the effectiveness and safety of adding metformin (Glucophage) to insulin therapy in the treatment of adolescents with type 1 diabetes (T1D). The study showed that the use of metformin in these patients resulted in improved blood glucose control and body mass index (BMI) with an increased risk of...
Read MoreIs the use of sodium-glucose cotransporter 2 inhibitors related to the occurrence of eye diseases in patients with type 2 diabetes?
In a nutshell This study investigated the link between sodium-glucose cotransporter 2 inhibitors (SGLT2is) and eye (ocular) diseases in patients with type 2 diabetes (T2D). The data showed that there was no link between the occurrence of eye diseases and SGLT2is in these patients. Some SGLT2is such as ertugliflozin (Steglatro) and empagliflozin...
Read MoreEvaluating the long-term outcomes of encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutated advanced melanoma.
In a nutshell This study reported the long-term effectiveness and safety of encorafenib (Braftovi) alone or in combination with binimetinib (Mektovi) or vemurafenib (Zelboraf) alone in patients with BRAF-mutated advanced melanoma. The data showed that the encorafenib plus binimetinib combination lead to long-term effectiveness and no new safety...
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