In a nutshell This study evaluated the effectiveness and safety of transanal (ta) versus laparoscopic (lap) total mesorectal resection (TME) for the treatment of patients with stage I-III rectal cancer (RC). The data showed that experienced surgeons can safely perform taTME in these patients. Some background Rectal cancer (RC) is one of the most...
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Evaluating the effectiveness of abemaciclib alone or in combination with tamoxifen in patients with HR+, HER2– metastatic breast cancer resistant to hormone therapy.
In a nutshell This study evaluated the effectiveness of abemaciclib (Verzenio) alone or in combination with tamoxifen (Nolvadex) in patients with hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer (BC) resistant to hormone therapy. The data showed that abemaciclib in combination with tamoxifen was more effective in improving...
Read MoreIs there evidence to support the effectiveness and safety of nutrient supplementation for control of blood glucose and management of insulin resistance in type 2 diabetes?
In a nutshell This review analyzed the effectiveness and safety of nutrient supplements for the control of blood glucose and insulin resistance in patients with type 2 diabetes (T2D). The authors concluded that there is currently a lack of sufficient clinical evidence to support the use of nutrient supplements for blood glucose control and improved...
Read MoreCan remission be increased in patients with rheumatoid arthritis by using more biologics and less corticosteroids under real-life conditions?
In a nutshell This study evaluated the 7-year follow-up remission rate and maintenance in patients with rheumatoid arthritis (RA) under real-life conditions and identified factors related to long-term remission. The authors concluded that at 7 years nearly twice as many patients were in remission than at 1 year of follow-up and those patients had mainly...
Read MoreEvaluating the effectiveness of transanal endoscopic microsurgery for the treatment of early rectal cancer in patients over 60 years old with high surgical risk.
In a nutshell This study evaluated the effectiveness of transanal endoscopic microsurgery (TEM) for the treatment of early rectal cancer (RC) in patients over 60 years old with high surgical risk. The data showed that TEM is a reliable and effective treatment option in high-risk patients over 60 years old. Some background Rectal cancer (RC) is one of...
Read MoreEvaluating the effect of patient-reported physical and mental health status before PCI/CABG on their long-term outcomes
In a nutshell This study evaluated the effect of patient-reported physical and mental health status before revascularization procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) on their long-term outcomes in patients with coronary artery disease (CAD). The data showed that...
Read MoreComparing the effects of a ketogenic diet versus a Mediterranean diet on glucose control in patients with prediabetes and type 2 diabetes.
In a nutshell This study compared the effects of a ketogenic diet (KD) versus a Mediterranean diet (MD) on glucose control in patients with prediabetes and type 2 diabetes (T2D). The data showed that the less restrictive MD was as effective in controlling glucose as a KD and likely more likely to be maintained in the long term. There...
Read MoreEvaluating the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected NSCLC.
In a nutshell This study evaluated the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected non-small cell lung cancer (NSCLC). The authors concluded that the combination of cisplatin (Platinol)-vinorelbine (Nevelbine) improved the outcomes of these patients. Also, the...
Read MoreEvaluating the effectiveness of different ovarian stimulation protocols for patients with poor ovarian response.
In a nutshell This study evaluated the effectiveness of different ovarian stimulation protocols for patients with poor ovarian response (POR). The data showed that delayed start gonadotropin-releasing hormone (GnRH) antagonist and microdose GnRH agonist were the two most effective regimens for the treatment of these patients. Some background Many...
Read MoreComparing the effectiveness and safety of combined therapy of atezolizumab with nab-paclitaxel in patients with triple negative breast cancer
In a nutshell The study compared the effectiveness and safety of atezolizumab (Tecentriq) and nab-paclitaxel (Abraxane) combined therapy with nab-paclitaxel alone in patients with triple-negative breast cancer (TNBC). The study found that combined therapy was more effective than single therapy but it had more serious side effects in these...
Read MoreEvaluating the effectiveness of massage therapy for chemotherapy-induced nerve disease
In a nutshell The study evaluated the effectiveness of massage therapy for chemotherapy-induced peripheral neuropathy (CIPN) in patients with breast and gastrointestinal (GI) cancer. The main finding of the study was that intensive massage therapy 3 times a week showed promising results in these patients. Some background There are many...
Read MoreEvaluating the effectiveness of massage therapy for chemotherapy-induced nerve disease
In a nutshell The study evaluated the effectiveness of massage therapy for chemotherapy-induced peripheral neuropathy (CPIN) in patients with breast and gastrointestinal (GI) cancer. The main finding of the study was that intensive massage therapy 3 times a week showed promising results in these patients. Some background There are many cancer...
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