In a nutshell The study evaluated the effectiveness of three exercise programs in improving quality of life (QOL), pain, and lymphedema among breast cancer (BC) survivors. The study found that joint mobility exercise (JME) combined with progressive resistance exercise (PRE) showed promising results in improving QOL and lymphedema after BC...
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Evaluating the effectiveness and safety of Q-122 for menopausal symptoms in women with breast cancer taking hormonal treatment
In a nutshell The study evaluated the effectiveness and safety of Q-122, a new non-hormonal oral treatment for menopausal symptoms in women with breast cancer taking hormonal therapy. The study found that Q-122 is effective and safe in treating menopausal symptoms in these patients. Some background The treatment for hormone receptor-positive...
Read MoreEvaluating the effectiveness and safety of two consecutive cycles of single embryo transfer versus one cycle of double embryo transfer in infertile women.
In a nutshell This study evaluated the effectiveness and safety of two consecutive cycles of single embryo transfer (SET) versus one cycle of double embryo transfer (DET) in infertile women. The data showed that two consecutive cycles of SET significantly reduced the rate of multiple births, improved the maternal and neonatal side effects, and showed a...
Read MoreEvaluating the effectiveness and safety of mFOLFOXIRI chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer
In a nutshell This study evaluated the effectiveness and safery of administering modified (m) FOLFOXIRI (folinic acid, fluorouracil, irinotecan, oxaliplatin) chemotherapy with or without radiotherapy before surgery in patients with locally advanced rectal cancer (LARC). The results showed that this treatment was safe and improved survival without disease...
Read MoreComparing the frequency and severity of nerve disease with eribulin versus paclitaxel before surgery in women with breast cancer
In a nutshell The study compared the frequency and severity of neuropathy (nerve damage) eribulin (Halaven) with paclitaxel (Taxol) given before surgery in women with operable breast cancer (BC). The study found that the frequency and severity of neuropathy were reduced in patients who received eribulin than in patients who received...
Read MoreCan biologic treatments influence the occurrence of infections in patients with rheumatoid arthritis?
In a nutshell This study compared the occurrence of infections and identified their risk factors in patients with rheumatoid arthritis (RA) that were treated with tofacitinib (Xeljanz) against those given a tumor necrosis factor inhibitor (TNFi). The data showed that serious and non-serious infections were higher in patients that received...
Read MoreEvaluating combined treatment of venetoclax and gilteritinib for relapsed or refractory acute myeloid leukemia with the FLT3 mutation.
In a nutshell This study evaluated the tolerability and effectiveness of combined therapy using venetoclax (Venclexta) and gilteritinib (Xospata) in patients with relapsed or refractory (r/r) acute myeloid leukemia (AML) with the FLT3 (FMS-related tyrosine kinase 3) mutation. The data showed that a combination of venetoclax and gilteritinib potentially...
Read MoreHow effective and safe is dapagliflozin as an add-on therapy to insulin in patients with type 1 diabetes?
In a nutshell This study evaluated the most effective and safe dose of dapagliflozin (Farxiga) as an additional treatment to insulin in patients with type 1 diabetes (T1D). The authors concluded that 10 mg of dapagliflozin as an add-on to insulin treatment resulted in improved blood glucose (sugar) control, reduced insulin dosage, and body...
Read MoreEvaluating the safety and effectiveness of FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of metastatic colorectal cancer
In a nutshell This study evaluated the effectiveness and safety of FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus bevacizumab (Avastin) with or without atezolizumab (Tecentriq) on the outcomes of patients with metastatic (m) colorectal cancer (CRC). The study showed that adding atezolizumab to FOLFOXIRI plus...
Read MoreEvaluating the effectiveness and safety of ivabradine in combination with beta-blockers in patients with stable angina.
In a nutshell This study evaluated the effectiveness and safety of ivabradine (Procoralan) in combination with beta-blockers in patients with stable angina. The data showed that the combination of ivabradine plus beta-blocker therapy effectively reduced heart rate, angina symptoms, and the use of short-acting nitrates from the first month of treatment...
Read MoreEvaluating the optimal treatment regimens given before and after surgery in improving survival outcomes in patients with HER2-positive breast cancer.
In a nutshell This study evaluated the optimal treatment regimens given before and after surgery in terms of improving the survival outcomes in patients with human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC). The data showed that chemotherapy plus trastuzumab (Herceptin) and pertuzumab (Perjeta) was the best treatment...
Read MoreEvaluating the effects of metformin and exenatide on pregnancy rate and pregnancy outcomes in overweight or obese infertile women with PCOS.
In a nutshell This study compared the effects of metformin (Glucophage) and exenatide (Byetta) on pregnancy rate and pregnancy outcomes in overweight or obese infertile women with polycystic ovary syndrome (PCOS). The data showed that 12 weeks of exenatide treatment before pregnancy improved spontaneous pregnancy in these women. Some background...
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