In a nutshell This study compared the effectiveness and safety of ultra-rapid lispro (URLi; LyumjevTM) to lispro (Humalog) in patients with type 1 diabetes (T1D) on continuous subcutaneous insulin infusion (CSII). The authors concluded that URLi was similarly effective and provided improved postprandial glucose (PPG) control with reduced hypoglycemia in...
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Can insulin pump technology help prevent low blood sugar in patients with T1D?
In a nutshell This study evaluated whether the ‘suspend-before-low’ feature of automatic insulin pumps prevented hypoglycemia (HG) in patients with Type 1 diabetes (T1D). The authors concluded that this feature successfully reduced the rate of HG and was not associated with increased side effects. Some background The goal of...
Read MoreLooking for people with type 1 diabetes to try an artificial pancreas
In a nutshell This clinical trial is investigating the effects of an artificial pancreas (AP) system on brain function in older adults with type 1 diabetes (T1D). The main outcome to be measured will be change in alternate fuel uptake by the brain during hypoglycemia (dangerously low blood glucose). The details Glucose is used as fuel by the brain and...
Read MoreSearching for adults and children with type 1 diabetes to test the hybrid closed loop insulin delivery system
In a nutshell This trial will evaluate the safety and effectiveness of the Hybrid Closed Loop (HCL) system in adult and pediatric patients with type 1 diabetes. The primary outcome of this study will be a change in HbA1c levels (average blood glucose over 3 months). The details HCL systems are a diabetes management strategy. They are composed of...
Read MoreDoes a low carbohydrate diet improve blood glucose control in type 1 diabetes?
In a nutshell This study investigated if a low carbohydrate diet improved glycemic control (blood sugar) and cardiovascular (heart and circulatory system) parameters in type 1 diabetes patients. They found that a low carbohydrate diet resulted in improved glycemic control with no effect on cardiovascular markers. Some background Glycemic...
Read MorePump it up – does diluting insulin aspart quicken its action in type 1 diabetes?
In a nutshell This study investigated the effect of diluting insulin aspart (B28Asp human insulin) in children aged 3-6 with type 1 diabetes. Some background Insulin is typically the first treatment for type 1 diabetes patients. One of the methods of delivery is via an insulin pump. In closed-loop insulin delivery, blood glucose is...
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