In a nutshell This article reviewed the NCCN guidelines for the treatment of chronic myeloid leukemia in children and in pregnant women. Some background The majority of CML patients are diagnosed when older (an average age of 65). Roughly 36.5% of patients are younger, and are diagnosed at reproductive age or in childhood. It is important to...
Read MoreIn a nutshell This article examined the evidence and made recommendations about weight loss in obese patients with type 2 diabetes (T2D). Some background Obesity is a common condition in people with T2D. Managing obesity in these patients can delay pre-diabetes advancing to T2D. Obesity management can also be helpful in treating T2D. Lifestyle...
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In a nutshell This review outlined guidelines for the treatment of acute myeloid leukemia (AML). Some background In AML, too many stem cells (immature blood cells) develop into abnormal red blood cells, white blood cells, or platelets (cells involved in clotting). Treatment options vary based on the age and condition of the patient, and on the...
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In a nutshell This study reviewed updated guidelines for the use of radiotherapy following mastectomy (surgical removal of the breast) in breast cancer. Some background Post-mastectomy radiation therapy (PMRT) is widely accepted for patients with four or more involved axillary (underarm) lymph nodes. The axillary lymph nodes are the first...
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In a nutshell This study reviewed the current treatment options for chronic lymphocytic leukemia. Some background Chronic lymphocytic leukemia (CLL) is a common form of leukemia in Western countries. Treatment options for CLL depend on the stage of the disease (the severity) and the overall health and fitness of the patient. Patients with...
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In a nutshell The authors aimed to identify the recommended treatments for prostate cancer in men over the age of 70 years. The authors concluded that treatments for local and advanced prostate cancer in elderly men should be individualized, with focus on the health of the patient, to determine the appropriate treatment course. Some background...
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In a nutshell The authors aimed to determine guidelines for the treatment of relapsing, metastatic, and hormone-resistant prostate cancer. Some background Metastatic prostate cancer (advanced cancer) is cancer that has spread outside of the prostate to other organs of the body, despite treatment. Hormone therapy is the standard...
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In a nutshell In this study the Clinical Practice Guidelines in Oncology (NCCN Guidelines) in melanoma updated the 2016 recommendations on therapy after surgery and treatment of in-transit disease (when cancer cells are almost reaching the lymph nodes). Some background Melanoma incidence has been rising rapidly. Patient outlook and treatment...
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In a nutshell These guidelines examined the evidence and presented recommendations for the treatment of type 2 diabetes with oral glucose-lowering drugs. It was concluded that metformin (Glucophage) was suitable for most patients, and that some may require an additional drug. Some background Type 2 diabetes (T2D) is a progressive...
Read MoreIn a nutshell This review provided guidelines relating to the treatment of nodular lymphocytic-predominant Hodgkin lymphoma (NLPHL). The authors concluded that appropriate treatment varied by age, disease-stage and the presence of relapse. Some background NLPHL is the rarer form of HL. It is characterized by the presence of atypical white...
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In a nutshell The review summarizes recent clinical trials and provides up to date guidelines on the detection, treatment and follw-up of advanced non-small-cell lung cancer (NSCLC). Some background Lung cancer is the leading cause of cancer-related deaths globally with NSCLC as the most common subtype of lung cancer. The success...
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In a nutshell This study summarized key guidelines for the diagnosis, treatment, and follow-up of classical Hodgkin lymphoma. Some background Hodgkin lymphoma (HL) is a cancer of the lymph system. Classical HL is the most common form and considered very treatable. It mostly occurs in young adults aged 20 to 34 years, but is also seen in adults...
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