In a nutshell This study summarizes key guidelines on the first-line management of acute myeloid leukemia (AML). Some background AML is a type of cancer in which the bone marrow makes abnormal myeloblasts (a type of white blood cell). An estimated 21,380 people will be diagnosed with AML in 2017. The average age at diagnosis is 67 years. As the...
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In a nutshell This article reviewed the NCCN guidelines for the treatment of classical Hodgkin lymphoma in adults 18 years of age or older. Some background Hodgkin lymphoma (HL) is generally considered a curable disease. Most HL occurs in young people between 15 and 30 years old. The most common treatments are chemotherapy and radiation....
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In a nutshell This study examined the alcohol consumption of females and males prior to undergoing assisted reproduction, to determine if it negatively impacted the chances of a live birth. This study did not reveal any association between alcohol consumption and the likelihood of achieving a live birth following assisted reproduction. Some...
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In a nutshell This review discussed the treatment options for older adults with chronic lymphocytic leukemia. This article recommends that CLL patients should have a fitness test before starting treatments to determine which treatment would suit them best. Some background Chronic lymphocytic leukemia (CLL) is a blood and bone marrow disease....
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In a nutshell This study reviewed the recommendations for the treatment and management of patients with multiple myeloma who are not able to undergo stem cell transplantation. Some background Multiple myeloma most frequently affects older patients. The standard treatment option is high-dose chemotherapy followed by stem cell transplantation (SCT)....
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In a nutshell This study reviewed treatment recommendations for elderly diffuse large B-cell lymphoma patients. Some background Diffuse large B-cell lymphoma (DLBCL) is the most common form of NHL in older patients. Many of these patients are over the age of 65. Chemotherapy is the standard treatment option for DLBCL. Many chemotherapies...
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In a nutshell This study reviewed updated guidelines for the staging and treatment of diffuse large B-cell lymphoma (DLBCL). Some background DLBCL accounts for 30%–58% of non-Hodgkin lymphomas. In recent years there have been improvements in the treatment of DLBCL. The European Society for Medical Oncology (ESMO) recently gathered a...
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In a nutshell This review outlined the current recommended treatment options for different stages of Hodgkin Lymphoma as well as highlighted promising new experimental drugs. Some background Hodgkin Lymphoma (HL) is generally considered a curable disease. Over 90% of patients diagnosed with early stage favorable HL will be cured. However, there...
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In a nutshell This study provided updated guidelines and recommendations for the staging, response assessment, and follow-up of patients with non-Hodgkin lymphoma (NHL). Some background Careful staging of lymphoma is essential, as this provides the basis for treatment decisions. The criteria for NHL staging and the tests used to diagnose, stage,...
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In a nutshell This study reviewed the updated NCCN guidelines for the treatment of metastatic (spread to other parts of the body) melanoma. Some background New treatments have been developed in recent years for metastatic melanoma, particularly targeted and immunotherapies. These treatments are leading to improved response and survival in these...
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In a nutshell This study provided 7 new recommendations for the management of Peyronie's disease (PD) based on recent evidence. Some background Peyronie's disease (PD) is a condition in which scar tissue, called plaque, develops along the shaft of the penis. These plaques cause the penis to curve, particularly during erections, which can...
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In a nutshell This study summarized key guidelines for the diagnosis, treatment, and follow-up of adult acute lymphoblastic leukemia (ALL). Some background ALL is a type of cancer in which the bone marrow makes too many lymphoblasts (a type of early white blood cell). A better understanding of ALL diagnosis, risk factors, treatment, and...
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