In a nutshell This study investigated if mild ovarian stimulation is as effective as conventional stimulation in vitro fertilization (IVF). They found that mild ovarian stimulation provides greater safety and lower cost, in addition to comparable success rates. Some background A part of the IVF process, women undergo a procedure to harvest...
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What anti-diabetic drugs are safe and effective in treating gestational diabetes?
In a nutshell This study investigated the safety and effectiveness of different drugs used to treat gestational diabetes. They found that metformin (Glucophage) is associated with fewer pregnancy complications than glyburide (Glynase), however it is less effective at managing blood sugar levels. Some background Gestational diabetes...
Read MoreGuidelines for the surgical management of female SUI
In a nutshell This study outlined guidelines for the surgical management of stress urinary incontinence (SUI). Some background Stress urinary incontinence (SUI) is the involuntary urine leakage during exertion, sneezing, coughing, lifting or any other physical activity. It has been estimated that the prevalence of SUI could be as high as...
Read MoreESMO Guidelines for mantle cell lymphoma
In a nutshell This study presented guidelines for the treatment and follow-up of mantle cell lymphoma presented by the European Society for Medical Oncology. Some background Mantle cell lymphoma (MCL) is a rare but usually aggressive type of non-Hodgkin lymphoma. Patients often experience multiple relapses after first- and second-line...
Read MoreRecommendations for second-line therapy in men with hormone-resistant prostate cancer
In a nutshell This review outlined the opinions of the American Society of Clinical Oncology for the treatment of hormone therapy resistant men with prostate cancer. Some background Advanced prostate cancer is cancer that has spread outside the prostate gland into surrounding organs. In some cases, cancer can become hormone-resistant. This is when...
Read MoreUpdate on guidelines for the use of adjuvant chemotherapy and targeted therapy in breast cancer patients.
In a nutshell This report summarized updates made to the guidelines for treatment of HER2-positive breast cancer with adjuvant chemotherapy and targeted therapy. Some background Adjuvant chemotherapy (treatment after surgery) is often used to prevent cancer recurrence. Chemotherapy involves agents that work to kill cancer cells in the body....
Read MoreRecommendations on adjuvant therapy for patients with early stage non-small-cell lung cancer
In a nutshell This article presents updated guidelines on treating non-small cell lung cancer patients with adjuvant (following surgery) chemotherapy or radiation. The authors provide recommendations on when to use adjuvant therapy based primarily on disease stage. Some background Cancer patients who have tumors removed by surgery often undergo...
Read MoreGuidelines for the use of hormone therapy in hormone receptor-positive patients with metastatic breast cancer.
In a nutshell This report aimed to develop recommendations for endocrine therapy in women with hormone receptor-positive metastatic breast cancer. Some background Endocrine therapy, also known as hormone therapy (HT) is used to treat hormone receptor (HR) positive metastatic breast cancer (MBC). HR positive MBC depends on the hormones estrogen or...
Read MoreGuidelines on the management of diabetes in pregnancy
In a nutshell These guidelines presented recommendations for the management of diabetes in pregnancy. It was concluded that counselling before pregnancy, appropriate care during pregnancy, and follow-up after delivery is needed. Some background Diabetes in pregnancy is increasing in the United States. Most of this is due to gestational diabetes...
Read MorePost-treatment long-term follow up for patients with Hodgkin lymphoma
In a nutshell The authors performed a review of previously published articles on follow-up care for patients with Hodgkin lymphoma. The authors concluded that follow-up treatment should be different depending on how long it has been since treatment, and the types of treatment received. Some background Hodgkin lymphoma (HL) is generally considered...
Read MoreExercise recommendations following stroke
In a nutshell This review includes recommendations on exercise and physical activity for stroke patients. The authors concluded that exercise programs can greatly increase quality of life for stroke patients. Some background Stroke patients often experience long term disability and cannot live independently due to mental and physical disabilities....
Read MoreContinuous glucose monitoring improves glycemic control in patients with type 1 diabetes
In a nutshell This study investigated the effect of continuous glucose monitoring (CGM) in managing blood sugar levels in patients with type 1 diabetes treated with multiple daily insulin injections. They found CGM resulted in a clinically meaningful improvement in glycemic (blood sugar) control. Some background Glycemic control is critical for...
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