In a nutshell This study reviewed the effect of high-dose vitamin D2 (ergocalciferol) supplementation on delaying the onset of type 1 diabetes (T1D) in children and adolescents with newly diagnosed T1D. The authors recommended maintaining a safe and effective high-dose vitamin D2 concentration of 30-60 ng/mL for delaying the onset of T1D in...
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In a nutshell These guidelines aimed to update treatment options for patients with Philadelphia chromosome-positive (Ph+) and negative (Ph-) acute lymphoblastic leukemia (ALL). Some background Acute lymphoblastic leukemia (ALL) represents 75% to 80% of acute leukemia among children and so is the most common form of childhood leukemia. It represents...
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In a nutshell This study reviewed the surgical management of benign prostatic hyperplasia (BPH). Some background Benign prostatic hyperplasia (BPH) is a condition in which the prostate grows larger than normal. The prostate can then squeeze the urethra (the tube that drains the bladder) causing problems with urination. Medical...
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In a nutshell This study reviewed the initial management of benign prostatic hyperplasia (BPH). Some background BPH is a condition in which the prostate grows and can compress the urethra (the tube that passes urine out of the bladder), leading to difficulty passing urine. Symptoms include needing to urinate frequently,...
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In a nutshell These guidelines reviewed current recommendations on treating newly diagnosed classic Hodgkin lymphoma (cHL) in children and young adults, and cHL which has returned after previous treatment. Some background Hodgkin lymphoma is cancer of the lymph nodes, which are part of the immune system. It involves cancerous versions of B cells,...
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In a nutshell This study described the updates to the National Comprehensive Cancer Network (NCCN) skin melanoma guidelines. Some background Melanoma is one of the most aggressive forms of skin cancer. Patients often have a biopsy of a suspected melanoma to evaluate the severity of the tumor. Treatment for melanoma includes surgery to remove the...
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In a nutshell This article aimed to outline updates to the National Comprehensive Cancer Network (NCCN) guidelines for the treatment of acute myeloid leukemia (AML). Some background The NCCN Guidelines for AML provide recommendations for the diagnosis and treatment of AML. The recommendations are based on clinical...
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In a nutshell This study reviewed the current NCCN guidelines for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC). Some background Metastatic castration-resistant prostate cancer (mCRPC) is an aggressive form of PC that has spread and is no longer responsive to hormonal therapy such as androgen deprivation...
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In a nutshell These guidelines reviewed current best practices in treating male infertility. Some background Male infertility affects half of all couples with infertility. Low sperm count or quality are the most common signs of male infertility. Medical organizations offer guidelines on how to treat male infertility. Methods &...
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In a nutshell These guidelines reviewed appropriate testing for men in couples with infertility. Some background Male infertility contributes to half of all cases of infertility. Identifying the cause of infertility is the first step towards managing it. There is ongoing research on the best methods of diagnosing infertility in men. Professional...
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In a nutshell This article reviewed current treatment options for treating multiple myeloma (MM). Some background MM is a form of cancer that originates from plasma cells (a form of white blood cell). This usually results in other normal cells of the bone marrow not working properly. MM is usually diagnosed in older patients. Despite...
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In a nutshell This review looked at pregnancy planning and care for women with type 1 diabetes (T1D). It found that preconception care and closely managing blood sugar during pregnancy can improve outcomes for both the mother and baby. Some background Pregnancy is always a time of bodily change. During pregnancy, blood glucose (sugar) and metabolism...
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