In a nutshell This phase 3 trial will investigate the safety and effectiveness of switching from rituximab (Rituxan/Mabthera) to DRL_RI in patients with rheumatoid arthritis (RA). The main outcome will be the rate of side effects and anti-drug drug antibodies (ADAs). This study is recruiting at several locations in the United...
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In a nutshell This study evaluates the outcomes associated with 2 years of treatment with rituximab + methotrexate versus methotrexate alone in rheumatoid arthritis patients. Some background Rheumatoid arthritis (RA) is a chronic inflammatory disease that typically affects the small joints in the hands and feet. It is an autoimmune disorder,...
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In a nutshell This trial compared the efficacy of 2 treatment regimens: methotrexate (MTX) monotherapy versus dual therapy of MTX plus biological drug in patients with early rheumatoid arthritis. Some background Rheumatoid arthritis (RA) is an autoimmune disease that occurs when the immune system mistakenly attacks the body’s own tissues, in...
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