In a nutshell This study evaluated the side effects in patients with type 2 diabetes (T2D) after treatment with glimepiride (Amaryl). The authors found that while glimepiride lowered mortality, the rate of most side effects was the same as other similar drugs. Some background Treatments for T2D aim to lower blood glucose...
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Ticagrelor – is it effective in preventing major cardiac events in patients with diabetes and coronary artery disease?
In a nutshell This study investigated ticagrelor (Brilique) added to aspirin in patients with coronary artery disease (CAD) and diabetes mellitus (DM). They found that ticagrelor reduced the risk of cardiac events in these patients. Some background Patients with diabetes have a higher risk of ischemic events (IEs). IEs are caused by a lack...
Read MoreSearching for patients with type 2 diabetes to test the effect of the drug efpeglenatide on heart disease
In a nutshell This trial is examining the effect of different doses of efpeglenatide on reducing cardiovascular (CV) disease in patients with type 2 diabetes (T2D). The main outcome to be measured is the occurrence of heart attacks, strokes or death from either of these events. The details Patients with type 2 diabetes (T2D) have a high risk of CV...
Read MoreRanolazine effectively controls chest pain in patients with type 2 diabetes mellitus
In a nutshell This study assessed the efficacy and safety of ranolazine (Ranexa) for the treatment of angina in patients with type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD). Some background Stable angina (or angina pectoris), is a type of chest pain or discomfort that usually occurs with physical activity or stress due to poor...
Read MoreManaging type 1 diabetes before and during pregnancy
Type 1 diabetes mellitus (T1DM) is associated with a higher risk of complications during pregnancy, both for the mother and the developing fetus. These can often be prevented with careful management. This article outlines current guidelines regarding T1DM management before and during pregnancy. Before pregnancy Pre-conception tests should...
Read MoreLifestyle Change and Mobility in Obese Adults with Type 2 Diabetes
In a nutshell The aim of the Look AHEAD (Action for Health in Diabetes) study was to asses the effect of an intensive lifestyle intervention on the body weight, fitness and mobility of overweight patients with type 2 diabetes (T2DM). Some background According to the Centers for Disease Control and Prevention more people may suffer from T2DM...
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