In a nutshell This study aimed at determining the efficacy and safety of using Teplizumab (an immunosuppressive drug) in preservation of C-peptide in type 1 diabetes. Some background Type 1 diabetes is believed to be caused by an autoimmune response where the body's own immune system attacks the beta cells of the pancreas and...
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In a nutshell This study aimed to determine the effect of treatment non-compliance on mortality rates in type 1 diabetes patients. Results showed that mortality was higher in patients who did not follow the prescribed treatment. Some background Approximately 10% of all diabetes mellitus patients have type 1 diabetes as a result of a complete lack...
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In a nutshell This study tested the efficacy of a new drug that may slow down the progression of type 1 diabetes. The main outcome was that Abatacept (Orencia) slowed down the decline in insulin production. Some background Type 1 diabetes is an autoimmune disease. This means that the body’s immune system begins to attack its own cells,...
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In a nutshell This study compared the efficacy of two insulin types in pregnant women with type 1 diabetes mellitus (T1DM). HbA1c levels were similar with either insulin type, while the fasting plasma glucose was lower with insulin detemir (Levemir) use. Some background Due to destruction of insulin-producing cells in the pancreas, T1DM patients...
Read MoreDaily insulin therapy is needed to maintain normal blood sugar levels (“glycemic control”) in all patients with type 1 diabetes mellitus (T1DM) and many patients with type 2 diabetes mellitus (T2DM). Insulin is usually given using insulin “pens” or insulin pumps. Glycemic control is assessed by frequent self-monitoring glucose...
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