In a nutshell This trial is aiming to assess the effectiveness and safety of a new drug (CIN-107) in patients with treatment-resistant hypertension (rHTN). The main outcome that will be measured is the change in blood pressure over a time-frame of 12-weeks. This trial is being carried out in the United States. The details Resistant...
Read More
In a nutshell This clinical trial will evaluate a telemonitoring system for measuring blood pressure (BP) in the management of hypertension. The main outcome will be any hypertension-related side effects such as visits to the hospital, deaths, heart attacks or strokes during the 6-month trial. The study will be recruiting in Jackson,...
Read More
In a nutshell This phase 3 trial will investigate the effects of aprocitentan for the treatment of resistant (difficult to control hypertension. The main outcome to be measured will be change in systolic blood pressure (SBP; the first number in the reading). The details Hypertension or high blood pressure is a common condition. To reduce BP,...
Read More
In a nutshell This review evaluates the role of autoimmune response as a cause of hypertension. In a nutshell This review evaluated new theories regarding the role of the immune response as a cause of hypertension. Some background There are multiple causes of hypertension (high blood pressure), including damage to...
Read More
In a nutshell This phase II trial evaluated the benefit of a new drug of the aldosterone synthase inhibitors class in the treatment of high blood pressure. Different doses of this new drug were compared to a placebo, and the effects on blood pressure were reviewed. Some background Aldosterone is a hormone produced by the adrenal glands, and a key...
Read More
In a nutshell The present study compares the effectiveness of two approaches – conservative and interventional – with relation to heart attack prevention in patients with a stable coronary heart disease (CAD). The conservative strategy consists of optimal drug therapy; the interventional approach is based on percutaneous coronary...
Read More
In a nutshell In this article, the use of nitrates in patients with coronary artery disease is reviewed in details. Both the benefits and limitations of nitrate therapy are discussed, as well as the effect of nitrate therapy on cardiac rehabilitation. Some background CAD (Coronary Artery Disease) is a major cause of death worldwide, but also...
Read More
